Neuropathology

Solve your toughest neurodiagnostic challenges with Neuropathology, 3rd Edition - the most information-packed, extensively illustrated neuropathology reference available! An expert author team presents more than 3,000 high-quality images - nearly all in full color - to provide unmatched visual guidance on the microscopic and gross pathologic presentation of a full range of neurologic diseases. New to this edition Understand the most recent developments in neurologic diseases and quickly identify important variants and outliers. Meet the needs of an aging population with expanded coverage of Alzheimer's and Parkinson's disease, motor neuron disorders, and prion diseases, as well as conditions such as multiple sclerosis. Apply the latest knowledge on molecular genetics and the growing role of genetic testing. Make optimal use of today’s functional imaging techniques with new information on PET, fMRI, and SPECT. Stay current with the newest diagnostic protocols and guidelines as endorsed by professional societies and national bodies, the most recent WHO classification of central nervous system diseases, and checklists for the handling and diagnosis of CNS tumors and tumor-like lesions. Get outstanding visual guidance with new full-color images, and new and updated drawings that clarify complex entities and concepts. Author Info By David Ellison, MD, PhD, MA, MSc, MBBChir, MRCP, FRCPath, David Ellison MD PhD MA MSc BChir MRCP(UK) FRCPath FRCPCH Chairman of Pathology & Director of Neuropathology St. Jude Children's Research Hospital Memphis, Tennessee, USA; Seth Love, MBBCh PhD FRCP FRCPath, Seth Love MBBCh PhD FRCP FRCPath Professor of Neuropathology Department of Neuropathology Institute of Clinical Neurosciences School of Clinical Sciences University of Bristol Frenchay Hospital Bristol, UK ; Leila Maria Cardao Chimelli, MD, Consultant Neuropathologist, Medical School of Ribeirao Preto, University of Sao Paulo, Brazil; Brian Harding, MD; James S. Lowe, BMedSci, BMBS, DM, FRCPath, Professor of Neuropathology, University of Nottingham Medical School, Honorary Consultant Pathologist, Queen's Medical Centre, University Hospital NHS Trust, Nottingham, UK; Harry V. Vinters, MD, Chief, Section of Neuropathology, UCLA School of Medicine, Los Angeles, CA, USA; Sebastian Brandner, Chair of Neuropathology, Institute of Neurology, Queen Square, London and William H Yong, MD, Assistant Professor of Pathology and Laboratory Medicine, UCLA Center for Health Sciences, Los Angeles, CA CONTENTS SECTION 1: PATHOLOGIC REACTIONS IN THE CNS Pathologic reactions in the CNS SECTION 2: PEDIATRICS Fetal and neonatal hypoxic-ischemic lesions Malformations Hydrocephalus Disorders that primarily affect white matter Neurodegenerative disorders of gray matter in childhood Miscellaneous pediatric disorders SECTION 3: VASCULAR DISORDERS Adult hypoxic and ischemic lesions Vascular disease and infarcts Hemorrhage SECTION 4: TRAUMA Head and spinal injuries SECTION 5: INFECTIOUS DISEASES Acute viral infections Chronic and subacute viral infections of the CNS Rickettsial infections Acute bacterial infections and bacterial abscesses Chronic bacterial infections and neurosarcoidosis Fungal infections Parasitic infections SECTION 6: DEMYELINATING DISEASES Multiple Sclerosis Other idiopathic demyelinating diseases SECTION 7: NUTRITIONAL AND METABOLIC DISORDERS Vitamin deficiencies Systemic metabolic disease Lysosomal and peroxisomal disorders Mitochondrial encephalopathies SECTION 8: TOXIC INJURIES Toxic injury of the CNS SECTION 9: NEURODEGENERATIVE DISEASES Classification and pathogenesis of neurodegenerative disorders Motor neuron disorders Parkinsonism and akinetic-rigid disorders Ataxic disorders Hyperkinetic movement disorders Dementias Prion diseases Thalamic and pallidal degenerations, neuroaxonal dystrophy and autonomic failure SECTION 10: NEOPLASMS Classification and general concepts of CNS neoplasms Astrocytic neoplasms Non-astrocytic gliomas Neuroepithelial neoplasms displaying neuronal features Embryonal neuroepithelial neoplasms of the CNS Neoplasms of the pineal gland Choroid plexus neoplasms Primary CNS lymphomas Peripheral nerve sheath neoplasms Meningiomas Neoplasms in the region of the pituitary fossa Miscellaneous neoplasms Neoplasms that spread to the CNS Paraneoplastic disorders