Neuroglia

Neuroglia, the third edition, is the long-awaited revision of the most highly regarded reference volume on glial cells. This indispensable edition has been completely revised, greatly enlarged, and enhanced with four-color figures throughout, all in response to the tremendous amount of new information that has accumulated since the previous edition seven years ago. Glial cells are, without doubt, the new stars in the neuroscience and neurology communities. Neglected in research for years, it is now evident that the brain only functions in a concerted action of all the cells, namely glia and neurons. Seventy one chapters comprehensively discuss virtually every aspect of normal glial cell anatomy, physiology, biochemistry and function, and consider the central roles of these cells in neurological diseases including stroke, Alzheimer disease, multiple sclerosis, Parkinson's disease, neuropathy, and psychiatric conditions. More than 20 new chapters have been added to accommodate the unprecedented growth of knowledge about the basic biology of glia and the sophisticated manner in which they partner with neurons in the course of normal brain function. Lavishly illustrated and meticulously edited, the third edition remains the most convenient and maximally useful reference available. This new edition is an essential reference for both newcomers to the field as well as established investigators. Neuroglia belongs on every neuroscientist's bookshelf and will be a great asset for educators and neurological clinicians as well. The long-awaited revision of this highly regarded reference volume on glial cells Lavishly illustrated Helmut Kettenmann, Research Group Leader, Cellular Neurosciences, Max Delbrueck Center for Molecular Medicine (MDC) Berlin, Germany, and Bruce R. Ransom, Warren and Jermaine Magnuson Professor and Chair, University of Washington School of Medicine, USA CONTENTS Section 1. Properties of Neuroglial Cells - Evolution of glial cells: insights from invertebrate glia - 1 Evolution of glial cells, Christian Klämbt - 2 Invertebrate glia, Marc R. Freeman - 3 Non-mammalian, vertebrate glia, Bruce Appel - Morphology, Ultrastructure and Identification - 4 ASTROCYTES AND EPENDYMAL GLIA, Andreas Reichenbach and Hartwig Wolburg - 5 Radial glial cells, Magdalena Götz - 6 STRUCTURE AND FUNCTION OF OLIGODENDROCYTES, Arthur M. Butt - 7 Schwann cells and myelin, by Rudolf Martini and Ágnes Patzkó - 8 Microglial Cells, Wolfgang J. Streit - 9 Pericytes of the central nervous system, Martin Krueger and Ingo Bechmann - 10 NG2 Cells (Polydendrocytes), Akiko Nishiyama - 11 Glial Cells in autonomic and sensory ganglia, Menachem Hanani and David C. Spray - Lineage and development - 12 Astrocyte Development, James E. Goldman - 13 Lineage and development: Oligodendrocytes, Katsuhiko Ono and Kazuhiro Ikenaka - 14 THE SCHWANN CELL LINEAGE: CELLULAR TRANSITIONS DURING DEVELOPMENT AND AFTER INJURY, Kristján R.Jessen and Rhona Mirsky - 15 MICROGLIA LINEAGE AND DEVELOPMENT, Marco Prinz - Physiological Properties - 16 Physiology of astrocytes: Ion channels and ion transporters, Christian Steinhäuser, Gerald Seifert, and Joachim W. Deitmer - 17 Release of gliotransmitters and transmitter receptors in astrocytes, Helmut Kettenmann and Robert Zorec - 18 Storage and release of non-transmitter signaling molecules from macroglia, OLIVER VON BOHLEN UND HALBACH AND KLAUS UNSICKER - 19 Physiology of microglia, Mami Noda & Alexei Verkhratsky - 20 Physiology of Oligodendrocytes, Vittorio Gallo and Jean-Marie Mangin - 21 Physiological Properties of NG2+ Glial Cells, Dwight E. Bergles - 22 Cytokine, chemokine and growth factor receptors and signaling, H.W.G.M. Boddeke, B.J.L. Eggen, and K.P.H. Biber - 23 Lipids, lipid mediators and other signaling molecules, Hideki Hayashi - 24 Gap Junctions and Hemichannels, Bruce R. Ransom and Christian Giaume - 25 Purinergic Mechanisms in Glial Cells, Margaret S. Ho and Shumin Duan - 26 Calcium signalling in neuroglia, Alexei Verkhratsky & Vladimir Parpura - 27 The Central Role of Astrocytes in Neuroenergetics, Pierre J. Magistretti and Luc Pellerin - Genomic Profiles - 28 The Astrocyte Transcriptome, Ditte Lovatt and Maiken Nedergaard - 29 Gene expression patterns of oligodendrocyte progenitor cells and oligodendroglia, Fraser J. Sim and Steven A. Goldman - Section 2. Functions of Neuroglial Cells - Astrocytes - 30 Outer Subventricular Zone Radial Glial Cells, Xiaoqun Wang and Arnold R. Kriegstein - 31 Glial control of synaptogenesis, Nicola J. Allen - 32 Neuron Migration and Axon Guidance, Andreas Faissner - 33 The Role of Glia in the Formation and Function of the Blood-Brain Barrier, Istvan Krizbai, Imola Wilhelm, Hans-Christian Bauer and Hannelore Bauer - 34 Control of the extracellular ionic environment and volume, Eva Syková - 35 Amino Acid Neurotransmitter Synthesis and Removal, Arne Schousboe, Lasse K. Bak, Karsten K. Madsen and Helle S. Waagepetersen - 36 Glycogen and Energy Metabolism, Angus Brown - 37 Astrocyte regulation of neurovascular control, Clare Howarth, Grant R.J. Gordon and Brian A. MacVicar - 38 Modulation of synaptic function and network activity, Andrea Volterra - 39 Astrocytic modulation of mammalian synapses circuits and behaviors, Michael M. Halassa and Philip G. Haydon - 40 Adult neurogenesis, Gerd Kempermann - 41 Modulation of neuroendocrine systems, Stéphane H. R. Oliet - Oligodendrocytes/Schwann cells - 42 Myelin, Impulse Conduction, and the Pathophysiology of Demyelination, Lakshmi Bangalore and Stephen G. Waxman - 43 Transcription factors in myelinating cells, Michael Wegner - 44 Factors controlling myelin formation , Ruth Stassart, Sandra Goebbels, Klaus-Armin Nave - 45 Regulation of Myelination by Functional Activity, R. Douglas Fields - 46 Iron and Glia, James R. Connor - Microglia - 47 Role of microglia in the normal brain, Frank Kirchhoff - 48 Factors controlling microglial activation, Uwe-Karsten Hanisch - 49 Roles of activated microglia, Kelly R Miller, Stefan Prokop & Frank L Heppner - 50 Immune functions of microglia, Trevor Owens - Section 3. Role of glial cells in disease - Mechanisms of glial injury - 51 Astrocyte Responses to CNS Injury and Disease, Michael V. Sofroniew - 52 Metabolic injury of oligodendrocytes and myelin, Peter K. Stys - 53 Interaction of microglia with neurons and astrocytes under lesioned neuronal conditions, Kazuyuki Nakajima and Shinichi Kohsaka - 54 Schwann cells and injury, Violetta Zujovic and Alexandros A. Lavdas - Recovery of Neural Function - 55 NERVE REGENERATION IN THE PERIPHERAL NERVOUS SYSTEm, Tessa Gordon and Olawale AR Sulaiman - 56 Nerve fibre regeneration in the CNS of higher vertebrates, Anita D. Buchli and, Martin E. Schwab - 57 GLIAL CELL TRANSPLANTATION FOR CNS REPAIR, Anne Baron-Van Evercooren and Rebecca Matsas - Diseases: - 58 Focal cerebral ischemia: The multifaceted role of glial cells, Ulrich Dirnagl, Bruce R. Ransom, and Josef Priller - Gliomas: - 59 Malignant Glioma, Dolores Hambardzumyan, Shannon Donnola and Rebecca Bish - 60 Glial tumors in Neurofibromatosis and Tuberous Sclerosis Complex, Anthony J. Apicelli and David H. Gutmann - Demyelinating diseases - 61 Multiple Sclerosis, Monika Bradl and Hans Lassmann - 62 Genetic mutations affecting myelin formation, Steven S. Scherer, M. Laura Feltri, and Lawrence Wrabetz - Neurodegenerative Diseases - 63 Amyotrophic Lateral Sclerosis (ALS), Rita Sattler and Jeffrey Rothstein - 64 Alzheimer's disease, Andrew Kraft and Jin-Moo Lee - 65 Huntington disease, Parkinson disease and other neurodegenerative diseases, Thomas Möller - Infectious diseases - 66 Glia in Bacterial and Viral CNS Infections, Gwenn Garden - Miscellaneous diseases 67 Neuroglia in Hepatic Encephalopathy, Mireille Bélanger, Javier Vaquero, and Roger F. Butterworth - 68 Microglia and Pain, Simon Beggs, Tuan Trang and Michael W. Salter - 69 Genetic disorders affecting astrocytes, Albee Messing and Michael Brenner - 70 Epilepsy, Detlev Boison - 71 Psychiatric Disorders, Josef Priller