Acquired Brain Injury in the Fetus and Newborn

Given the tremendous advances in the last five years in the understanding of acquired neonatal brain injury and in the care of affected newborn infants, this book provides a timely review for the practising neurologist, neonatologist and pediatrician. The editors take a pragmatic approach, focusing on specific populations encountered regularly by the clinician. They begin by addressing aspects of fetal neurology and the interpretation of fetal imaging studies. They then follow a “bench to bedside” approach to acquired brain injury in the preterm and term newborn infant in the next chapters. The contributors, all internationally recognized clinician scientists, provide the clinician reader with a state-of-the art review in their area of expertise. The final section of the book address special populations and concerns, areas that are largely overlooked in existing neurology textbooks. Each of these areas has seen considerable advances in the last five years and is of increasing relevance to the neurologist and neonatologist clinician. The comprehensive nature of each section (from basic science to acute clinical care to outcomes) should appeal broadly to scientists and allied health professionals working in neonatal neurology. Readership Paediatric neurologists, neonatologists, neurologists and paediatricians, clinicians in child development, child health researchers and allied health professionals (in physiotherapy, occupational therapy, speech therapy and psychology). Trainees in these areas. CONTENTS Section 1: Fetal Brain Injury 1. CLINICAL ASPECTS Adré DuPlessis (Boston, MA, USA) 2. IMAGING THE FETAL BRAIN Catherine Limperopoulos (Montreal, Canada) Section 2: Brain Injury in the Preterm Infant 3. MECHANISMS OF ACUTE AND CHRONIC BRAIN INJURY IN THE PRETERM INFANT Stephen Back (Portland OR, USA) 4. CLINICAL ASSESSMENT Helstrom Westas 5. IMAGING THE PRETERM BRAIN Serena Counsell (London, UK) 6. PROTECTING THE PRETERM BRAIN Terrie Inder and Christopher Smyser (St Louis, MO, USA) 7. SEIZURES IN THE PRETERM INFANT Hannah Glass (San Francisco, CA, USA) 8. OUTCOMES FOLLOWING BRAIN INJURY IN THE PRETERM Marilee Allen (Baltimore, MD, USA) Section 3: Brain Injury in the Term Infant 9. MECHANISMS OF NEURODEGENERATION IN THE NEONATAL BRAIN Frances J. Northington (Baltimore, MD, USA) 10. CLINICAL APPROACH TO NEONATAL ENCEPHALOPHY Jerome Yager (Edmonton, Canada) and Steve Miller (Vancouver, Canada) 11. IMAGING TERM INFANTS WITH SUSPECTED HYPOXIC-ISCHEMIC ENCEPHALOPHY Kenneth Poskitt (Vancouver, Canada) 12. PROTECTING THE TERM BRAIN Donna Ferriero (San Francisco, CA, USA) 13. SEIZURES IN THE TERM NEWBORN Linda de Vries (Utrecht, The Netherlands) 14. OUTCOMES FOLLOWING BRAIN INJURY IN THE TERM INFANT Bea Latal (Zurich, Switzerland) Section 4: Special Populations & Concerns 15. NEONATAL NEUROLOGY IN THE DEVELOPING WORLD Nicola Robertson (London, UK) 16. PERINATAL STROKE Yvonne Wu (San Francisco, CA, USA) 17. BRAIN INJURY IN NEWBORNS WITH CONGENITAL HEART DEFECTS Patrick McQuillen (San Francisco, USA), Steve Miller (Vancouver, Canada), Annette Majnemer (Montreal, Canada) 18. METABOLIC BRAIN INJURY (INBORN ERRORS, HYPOGLYCAEMIA, HYPERBILIRUBINEMIA) Linda De Meirleir (Brussels, Belgium) 19. THE NUTRITIONALLY DEPRIVED FETUS AND NEWBORN Michael Georgieff (Minneapolis, MN, USA) 20. ETHICAL CONSIDERATIONS IN FETAL AND NEONATAL NEUROLOGY Michael Shevell (Montreal, Canada)