Babies of women with diabetes are nearly five times more likely to be stillborn and almost three times more likely to die in the first three months. The incidence of gestational diabetes mellitus in the U.S. is high—between 3 and 7 percent—and rising. The condition is often complicated by other risk factors such as obesity and heart disease.
The Textbook of Diabetes and Pregnancy presents a comprehensive review of the science, clinical management, and medical implications of gestational diabetes mellitus, a condition with serious consequences that is on the increase in all developed societies. This new edition supports the latest initiatives and strategies of the International Federation of Gynecology and Obstetrics (FIGO) and adds chapters on noncommunicable diseases, obesity, bariatric surgery, and epidemiology outside Western cultures.
Written by a cadre of experts, the book provides a comprehensive, authoritative, and international view of gestational diabetes mellitus and will be invaluable to maternal-fetal medicine specialists, diabetologists, neonatologists, and a growing number of gynecologists and general physicians concerned with the management of noncommunicable diseases in pregnancy.
Features
Supports the latest initiatives by the International Federation of Gynecology and Obstetrics (FIGO)
Adds chapters on obesity, bariatric surgery, and epidemiology outside Western cultures
Compensates for cultural differences in lifestyle and their implications for diabetes
Features contributions by international experts in the field
Table of Contents
Introduction: Merging the Legacies and Hypotheses: Maternal Medicine Meets Fetal Medicine
Moshe Hod, Kypros Nicolaides, Hamutal Meiri, and Nicky Lieberman
History of Diabetic Pregnancy
David R. Hadden
Metabolism in Normal Pregnancy
Emilio Herrera and Henar Ortega-Senovilla
Intermediary Metabolism in Pregnancies Complicated by Gestational Diabetes
Bartolomé Bonet, María Bonet-Alavés, and Isabel Sánchez-Vera
Nutrient Delivery and Metabolism in the Fetus
William W. Hay, Jr., Paul J. Rozance, Stephanie R. Wesolowski, and Laura D. Brown
Pathogenesis of Gestational Diabetes Mellitus
Yariv Yogev
Autoimmunity in Gestational Diabetes Mellitus
Alberto de Leiva, Dídac Mauricio, and Rosa Corcoy
Epidemiology of Gestational Diabetes Mellitus
Yariv Yogev, Avi Ben Haroush, Moshe Hod, and Jeremy Oats
Genetics of Diabetic Pregnancy
Komal Bajaj and Susan J. Gross
Animal Models in Diabetes and Pregnancy Research
Catherine Yzydorczyk, Delphine Mitanchez, and Umberto Simeoni
Pathologic Abnormalities of Placental Structure and Function in Diabetes
Rhonda Bentley-Lewis, Maria Rosaria Raspollini, and Drucilla Roberts
The Great Obstetric Syndromes: The Roots of Disease
Rinat Gabbay-Benziv and Ahmet A. Baschat
Placental Origins of Diabesity and the Origin of Preeclampsia
Gernot Desoye and Berthold Huppertz
Diagnosis of Gestational Diabetes Mellitus
Donald R. Coustan and Boyd E. Metzger
Cost-Effectiveness of Screening and Management Programs for Gestational Diabetes Mellitus
Louise K. Weile, James G. Kahn, Elliot Marseille, and Nicolai Lohse
Changing Health Policy: From Study to National Policy
Ofra Kalter-Leibovici, Nicky Lieberman, Ronni Gamzu, and Moshe Hod
Ideal Weight Gain in Diabetic Pregnancy
Gerard H.A. Visser and Harold W. de Valk
Medical Nutritional Therapy for Gestational Diabetes Mellitus
Lois Jovanovic
Pharmacologic Treatment of Gestational Diabetes Mellitus: When to Start and What Agent to Use
Celeste P. Durnwald and Mark B. Landon
Gestational Diabetes Mellitus: The Consequences of Not Treating
Oded Langer
Gestational Diabetes Mellitus in Multiple Pregnancies
Matteo Andrea Bonomo and Angela Napoli
Glycemic Goals in Diabetic Pregnancy and Defining a "Good Control": Maternal and Fetal Perspective
Liran Hiersch and Yariv Yogev
Insulin Therapy in Pregnancy
Lois Jovanovic and John L. Kitzmiller
Use of Oral Hypoglycemic Agents in Pregnancy
Oded Langer
The Drug Dilemma of Oral Antidiabetic Agents in Pregnancy: Metformin
Yoel Toledano, Moshe Zloczower, and Nicky Lieberman
Facing the Noncommunicable Diseases’ Global Epidemic: The Battle of Prevention Starts In Utero the FIGO Challenge
Luis Cabero and Sabaratnam Arulkumaran
Links between Maternal Health and Noncommunicable Diseases
Anil Kapur
Diabetic Pregnancy in the Developing World
Eran Hadar, Eran Ashwal, and Moshe Hod
Managing Diabetic Pregnancy in China
Huixia Yang, Weiwei Zhu, and Rina Su
Gestational Diabetes Mellitus, Obesity, and Pregnancy Outcomes
Harold David McIntyre, Marloes Dekker-Nitert, Helen Lorraine Graham Barrett, and Leonie Kaye Callaway
Obesity Versus Glycemic Control: Which Contributes More to Adverse Pregnancy Outcome?
Amir Aviram and Yariv Yogev
Pharmacological Treatment for the Obese Gestational Diabetes Mellitus Patient
Fiona C. Denison and Rebecca M. Reynolds
Role of Exercise in Reducing the Risks of Gestational Diabetes Mellitus in Obese Women
Raul Artal
Role of Bariatric Surgery in Obese Women Planning Pregnancy
Ron Charach and Eyal Sheiner
Fetal Lung Maturity
Gian Carlo Di Renzo, Giulia Babucci, and Graziano Clerici
Monitoring during the Later Stage of Pregnancy and during Labor: Glycemic Considerations
Harold W. de Valk and Gerard H.A. Visser
Timing and Mode of Delivery
Salvatore Alberico and Gianpaolo Maso
Management of the Macrosomic Fetus
Federico Mecacci, Marianna Pina Rambaldi, and Giorgio Mello
Congenital Malformations in Diabetic Pregnancy: Prevalence and Types
Paul Merlob
Diabetic Embryopathy in the Preimplantation Embryo
Asher Ornoy and Noa Bischitz
Postimplantation Diabetic Embryopathy
Ulf J. Eriksson and Parri Wentzel
Fetal Malformations Detected with Magnetic Resonance Imaging in the Diabetic Mother
Tuangsit Wataganara
Continuous Glucose Monitoring in Pregnancy
Marlon Pragnell and Aaron Kowalski
Insulin Infusion Pumps in Pregnancy
Ilana Jaye Halperin and Denice S. Feig
Closed-Loop Insulin Delivery in Type 1 Diabetes Pregnancy
Zoe A. Stewart and Helen R. Murphy
Noninvasive Glucose Monitoring
Itai Ben-David and Pierre Singer
Reproduction and Its Impact on Health and Disease
Sara Ornaghi and Michael J. Paidas
Diabetes, Pregnancy, and the Developmental Origins of Health and Disease
Gerard H.A. Visser and Mark A. Hanson
Interventions to Improve Pregnancy Outcome in Obese Pregnancy: Implications for Mother and Child
Rahat Maitland and Lucilla Poston
Lifestyle Interventions to Reduce Risk of Diabetes among High-Risk Pregnant and Postpartum Women
Lisa Chasan-Taber
Can Fetal Macrosomia Be Predicted and Prevented?
Maria Farren and Michael Turner
Hypoglycemia in Diabetic Pregnancy
Graziano Di Cianni, Cristina Lencioni, Emilia Lacaria, and Laura Russo
Hypertensive Disorders and Diabetic Pregnancy
Jacob Bar, Moshe Hod, and Michal Kovo
Diabetic Retinopathy
Nir Melamed and Moshe Hod
Diabetic Nephropathy
Elisabeth R. Mathiesen, Lene Ringholm, and Peter Damm
Diabetic Ketoacidosis
Annunziata Lapolla and Maria Grazia Dalfrà
Thyroid Disease in Pregnancy
Yoel Toledano and Gabriella Solomon
Quality of Care for the Woman with Diabetes at Pregnancy
Alberto de Leiva, Rosa Corcoy, Alejandra de Leiva-Pérez, and Eulàlia Brugués
Early Pregnancy Loss and Perinatal Mortality
Kinneret Tenenbaum-Gavish, Anat Shmuely, and Moshe Hod
Short-Term Implications of Gestational Diabetes Mellitus: The Neonate
Delphine Mitanchez, Catherine Yzydorczyk, and Umberto Simeoni
Long-Term Outcomes after Gestational Diabetes Mellitus Exposure in the Offspring
Delphine Mitanchez, Catherine Yzydorczyk, and Umberto Simeoni
Metabolomics and Diabetic Pregnancy
Angelica Dessì, Roberta Carboni, and Vassilios Fanos
Fetal Growth Restriction: Evidence-Based Clinical Management
Eduard Gratacós and Francesc Figueras
