Genomic and Precision Medicine: Cardiovascular Disease

Table of Contents:
1. Overview:  A Systems Approach To Cardiovascular Medicine
2. Application of Human Genome Information to Clinical Practice
• Genome sequencing: new technologies, approaches, applications
• Clinical applications of whole-genome chromosomal microarray analysis
• Transcriptomics in the age of ultra high-throughput sequencing
• Quantitative Proteomics in Genomic Medicine
3. Translating genome information into clinical practice and human health
4. Big Data and Translational Bioinformatics Genomic and Personalized Medicine
• Biospecimen Banking linked to phenotype data
• Electronic Health Records
• Data Sharing and Privacy
5. Health Risk Assessment and Family History
6. Clinical Decision Support
7. Overview of Policy, Ethical and Social Considerations
8. Hypertension
9. Lipoprotein Disorders
10. Coronary Artery Disease and Myocardial Infarction
11. The Vulnerable Plaque and Acute Coronary Syndromes
12. Heart Failure
13. Hypertrophic Cardiomyopathies
14. Arrhythmias
15. Hemostasis and Thrombosis
16. Peripheral Arterial Disease
17. Congenital Heart Disease
18. Perioperative Genomics
19. Stroke
20. Novel Approaches to Cardiovascular Diagnostics
21. Cardiovascular Pharmacogenomics
22. Case Studies

Geoffrey S. Ginsburg, Duke Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, USA and Huntington F Willard, PhD, Director & Principal, Geisinger National Precision Health, North Bethesda, Maryland, USA