Molecular Biology

The last quarter of the 20th century saw major scientific revolutions in genetics and computer technology. This book reflects this massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. Molecular Biology, 2e, effectively introduces basic concepts followed by more specific applications as the text evolves. With the addition of Cell Press articles, the content is tied to current topics in the scientific community. David Clark , BA (honors)Christ's College Cambridge, 1973 PhD University of Brsitol (England), 1977, Southern Illinois University, Carbondale, Illinois, USA - Nanette Pazdernik , School of Medicine at Washington University, St. Louis, Missouri, USA CONTENTS Unit 1: Basic Chemical and Biological Principles Ch1 Cells and Organisms Ch2 Basic Genetics Ch3 DNA, RNA, and Protein Ch4 Genes, Genomes, and DNA Ch5 Manipulation of Nucleic Acids Unit 2: The Genome Ch6 Polymerase Chain Reaction Ch7 Cloning Genes for Analysis Ch8 DNA Sequencing Ch9 Genomics & Systems Biology Unit 3: The Central Dogma of Molecular Biology Ch10 Cell Division and DNA Replication Ch11 Transcription of Genes Ch12 Processing of RNA Ch13 Protein Synthesis Ch14 Protein Structure & Function Ch15 Proteomics: Global Analysis of Proteins Unit 4: Regulating Gene Expression Ch16 Regulation of Transcription in Prokaryotes Ch17 Regulation of Transcription in Eukaryotes Ch18 Regulation at RNA Level Ch19 Analysis of Gene Expression (Transcriptome) Unit 5: Subcellular Life Forms Ch20 Plasmids Ch21 Viruses Ch22 Mobile DNA Unit 6: Changing the DNA Blueprint Ch23 Mutations and Repair Ch24 Recombination Ch25 Bacterial Genetics Ch26 Molecular Evolution