This book is contemporary, topical and global in its approach, and provides an essential, comprehensive treatise on bovine tuberculosis and the bacterium that causes it, Mycobacterium bovis. Bovine tuberculosis remains a major cause of economic loss in cattle industries worldwide, exacerbated in some countries by the presence of a substantial wildlife reservoir. It is a major zoonosis, causing human infection through consumption of unpasteurised milk or by close contact with infected animals.
Following a systematic approach, expert international authors cover epidemiology and the global situation; microbial virulence and pathogenesis; host responses to the pathogen; and diagnosis and control of the disease.
Aimed at researchers and practising veterinarians, this book is essential for those needing comprehensive information on the pathogen and disease, and offers a summary of key information learned from human tuberculosis research. It will be useful to those studying the infection and for those responsible for controlling the disease.
Table of Contents
1: Bovine tuberculosis: worldwide picture
2: Mycobacterium bovis as the causal agent of human tuberculosis: Public Health Implications
3: Economics of bovine tuberculosis: a One Health issue
4: The Epidemiology of Mycobacterium bovis Infection in Cattle
5: Mycobacterium bovis molecular typing and surveillance
6: Bovine Tuberculosis in Other Domestic Species
7: Role of wildlife in the epidemiology of Mycobacterium bovis
8: Molecular virulence mechanisms of Mycobacterium bovis
9: The pathology and pathogenesis of Mycobacterium bovis infection
10: Innate immune response in bovine tuberculosis
11: Adaptive immunity
12: Immunological Diagnosis
13: Biomarkers in the Diagnosis of Mycobacterium tuberculosis Complex Infections
14: Vaccination of domestic and wild animals against tuberculosis
15: Managing Bovine Tuberculosis; Successes and Issues
16: Perspectives on global bovine TB control
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