Postoperative Nausea and Vomiting

Postoperative nausea and vomiting is an increasingly common and distressing problem faced by patients undergoing anesthesia that negatively affects their recovery and wellbeing and can result in significant increases in healthcare costs. Effective treatment strategies and relevant, up-to-date guidance are essential to manage postoperative nausea and vomiting in the perioperative setting. This practical, concise guide to the subject offers information on the history and mechanisms of postoperative nausea and vomiting, assessing and identifying risk factors, providing appropriate pharmacological and non-pharmacological treatment options, and implementing successful management strategies to tackle this issue. As a uniquely comprehensive study of the topic that provides much more detail than a chapter in a general anaesthesia textbook, this is an invaluable resource for anesthetists and physicians managing patients post-surgery.

    This is the only fully up-to-date book-length discussion of the topic, making it an invaluable resource for clinicians who regularly deal with patients experiencing PONV
    Provides guidance on both pharmacological and non-pharmacological treatment strategies, giving the reader a thorough and comprehensive understanding of the available options
    PONV is a growing problem, with incidences increasing over time and a growing need for effective treatment strategies, making this book increasingly relevant for healthcare practitioners

Table of Contents

List of contributors
Foreword Henrik Kehlet
Preface
1. History of postoperative nausea and vomiting Johan Raeder
2. Mechanisms of nausea and vomiting Anthony L. Kovac
3. Risk factors and their impact on PONV Anthony L. Kovac
4. Patients' experience and nursing perspective Vallire D. Hooper
5. Genomics and personalized medicine in PONV management Keith A. Candiotti, Enisa M. F. Carvalho and Ana C. Mavarez
6. Pharmacology of serotonin antagonists Jacob Nouriel and Gildasio De Oliveira
7. Pharmacology of histamine, muscarine and dopamine antagonists Tricia A. Meyer and Russell K. McAllister
8. Pharmacology of neurokinin antagonists and novel antiemetics Linda M. L. Lai, William K. K. Wu and Matthew T. V. Chan
9. Propofol and other sedatives as antiemetics Aaron Skolnik and Tong Joo Gan
10. Non-pharmacological management of PONV Anna Lee and Tony Gin
11. Combination antiemetics Jessica Carter, Amy Mauritz and Ashraf S. Habib
12. Management of postoperative nausea and vomiting in pediatric patients Imelda Tjia, Michelle Dalton and Mehernoor F. Watcha
13. Management of PONV in inpatients and ambulatory patients Brian Donnenfeld and Beverly K. Philip
14. PONV management: cost-effectiveness and patient outcome Paul S. Myles
15. PONV research: methodology, assessment and strength of evidence John Carlisle
16. Implementing PONV management guidelines Peter Kranke
Index.

Tong Joo Gan, Duke University Medical Center, Durham
Tong Joo Gan, MD MHS FRCA, is Professor and Chairman in the Department of Anesthesiology, Stony Brook University, Stony Brook, New York, USA.

Ashraf S. Habib, Duke University Medical Center, Durham
Ashraf S. Habib, MBBCh MSc MHSc FRCA, is Professor of Anesthesiology and Chief in the Division of Women's Anesthesia at Duke University Medical Center, Durham, North Carolina, USA.
Foreword

Henrik Kehlet
Contributors

Henrik Kehlet, Johan Raeder, Anthony L. Kovac, Vallire D. Hooper, Keith A. Candiotti, Enisa M. F. Carvalho, Ana C. Mavarez, Jacob Nouriel, Gildasio De Oliveira, Tricia A. Meyer, Russell K. McAllister, Linda M. L. Lai, William K. K. Wu, Matthew T. V. Chan, Aaron Skolnik, Tong Joo Gan, Anna Lee, Tony Gin, Jessica Carter, Amy Mauritz, Ashraf S. Habib, Imelda Tjia, Michelle Dalton, Mehernoor F. Watcha, Brian Donnenfeld, Beverly K. Philip, Paul S. Myles, John Carlisle, Peter Kranke