Interventional Oncology

Interventional oncology has emerged as an important specialty within cancer care, providing targeted therapy and palliative benefits without the side effects of chemotherapy, surgery and radiation. Covering the principles of current and emerging interventional oncology techniques and detailed diagnosis, staging and treatment algorithms, this book outlines the ways in which these image-guided therapies can inform cancer management strategies. Access to the most current information is vital in this rapidly growing and evolving area of practice. This new edition reflects the most recent clinical data on interventional oncology procedures. Chapters on image guidance and targeting, tumor ablation, embolotherapy, and response assessment have been updated to reflect major technological advances, and new material on microwave ablation and irreversible electroporation has been added. This invaluable resource for interventional radiologists provides essential education and guidance on the full range of minimally invasive image-guided procedures and their integration into comprehensive cancer care.

    New and updated chapters reflect the most current clinical data and information on interventional oncology procedures
    Features a dedicated section on palliative care, an essential aspect of cancer management
    Provides everything the interventional oncologist needs in one volume, without being too specialized or too general

Table of Contents

Part I. Principles of Oncology:
1. Interventional oncology: the fourth pillar of cancer care Michael C. Soulen and Jean-Francois H. Geschwind
Part II. Principles of Image-Guided Therapies:
2. Principles of radiofrequency and microwave tumor ablation Anthony M. Esparaz, S. Nahum Goldberg and Muneeb Ahmed
3. Principles of irreversible electroporation Govindarajan Srimathveeravalli and Stephen B. Solomon
4. Principles of high intensity focused ultrasound Aradhana M. Venkatesan and Bradford J. Wood
5. Principles of tumor embolotherapy and chemoembolization Hwan Jun Jae, Jae Hyung Park and Jin Wook Chung
6. Principles of radioembolization Vanessa L. Gates, Riad Salem and Robert J. Lewandowski
7. Principles of intraarterial infusional chemotherapy in the treatment of liver metastases from colorectal cancer Fidel David Huitzil Melendez and Nancy Kemeny
8. Imaging in interventional oncology: role of image guidance Francois Cornelis and Stephen B. Solomon
9. Novel developments in MR assessment of treatment response after locoregional therapy Kelly Fabrega-Foster, Neda Rastegar, Jean-Francois H. Geschwind and Ihab R Kamel
Part III. Organ-Specific Cancers - Primary Liver Cancers:
10. Assessment and triage of hepatocellular carcinoma Riccardo Lencioni
11. Image guided ablation of hepatocellular carcinoma Laura Crocetti, Maria Clotilde Della Pina, Dania Cioni and Riccardo Lencioni
12. Embolization of liver tumors: anatomy Hyo-Cheol Kim and Jin Wook Chung
13. Conventional chemoembolization and chemoembolization with drug-eluting beads: technique and future potential Julius Chapiro, Florian Nima Fleckenstein, Lynn Jeanette Savic and Jean-François H. Geschwind
14. 90Yttrium radioembolization for hepatocellular carcinoma Ryan M. Hickey, Riad Salem and Robert J. Lewandowski
15. Image-guided therapy of intrahepatic cholangiocarcinoma Michael C. Soulen and William S. Rilling
Part IV. Organ-Specific Cancers - Liver Metastases:
16. Colorectal masses: ablation Elena N. Petre, Stephen B. Solomon and Constantinos T. Sofocleous
17. Assessment, triage and chemoembolization for colorectal liver metastases Michael C. Soulen, Govindarajan Narayanan and Ursina Teitelbaum
18. Radioembolization for colorectal liver metastases Lourens Bester, Baerbel Meteling and David Boshell
19. Assessment, triage and liver-directed therapies for neuroendocrine tumor metastases Terence P. Gade and Michael C. Soulen
20. Preoperative portal vein embolization David Li and David C. Madoff
Part V. Organ-Specific Cancers - Extrahepatic Biliary Cancer:
21. Extrahepatic biliary cancer: stenting, brachytherapy and photodynamic therapy Vlastimil Valek and Tomas Andrasina
Part VI. Organ-Specific Cancers - Renal Cell Carcinoma:
22. Management of small renal masses Mansi A. Saksena, Debra A. Gervais, Michael C. Soulen and Peter R. Mueller
23. Embolotherapy in the management of renal cell carcinoma Ricardo Garcia-Monaco
Part VII. Organ-Specific Cancers - Chest:
24. Image-guided ablation in the thorax Erica S. Alexander and Damian E. Dupuy
Part VIII. Organ-Specific Cancers - Musculoskeletal:
25. Percutaneous ablation of painful metastases involving bone Matthew R. Callstrom and A. Nicholas Kurup
26. Cementoplasty and musculoskeletal interventions Sean Tutton and Alexis Kelekis
Part IX. Organ-Specific Cancers - Prostate:
27. Prostate ablations Francois Cornelis, Jeremy C. Durack, Behfar Ehdaie, J. Coleman and Stephen B. Solomon
Part X. Specialized Interventional Techniques in Cancer Care:
28. Vascular access: venous and arterial ports Thierry de Baère and Eric Desruennes
29. Palliative care and symptom management Drew A. Rosielle, Melissa Atwood, Sean Marks and William S. Rilling
30. CT-guided neurolysis for cancer-related abdominal and pelvic pain Ashraf Thabet
31. Palliative procedures for ascites and effusion Hooman Yarmohammadi.

Jean-Francois H. Geschwind, Yale University School of Medicine, Connecticut
Jean-Francois H. Geschwind, MD is the new Chairman of Radiology and Biomedical Imaging at Yale University School of Medicine, Radiologist in Chief at Yale-New Haven Hospital and also a Professor of Radiology and Oncology at Yale University School of Medicine. Originally from Paris, Dr Geschwind received his medical degree in 1991 from Boston University School of Medicine. He completed his residency training in Diagnostic Radiology at the University of California, San Francisco and his Fellowship in Vascular and Interventional Radiology in 1998 at The Johns Hopkins University School of Medicine where he remained on faculty and as the Chief of Vascular and Interventional Radiology since 2002. Dr Geschwind is recognized as a key expert in the field of liver cancer and he has focused his research on developing new therapies for liver cancer. He is the author or co-author of more than 400 published manuscripts and abstracts, primarily on subjects dealing with liver cancer, and is also the recipient of numerous national and international awards and grants for his research in this field. As lead or co-investigator on more than 50 clinical trials, Dr Geschwind's research has been published in many top peer-reviewed journals, including the Journal of Clinical Oncology, Radiology, Hepatology, Clinical Cancer Research, Cancer Research and Annals of Surgery. Dr Geschwind serves on the editorial board of many journals and is a consultant to the Editor of Radiology as well as a reviewer for numerous radiology, hepatology and oncology journals. He is the current chairman of the World Conference on Interventional Oncology Board of Directors and is the chair of the Interventional Oncology Lecture Series for the RSNA. He is a Fellow of both the Society of Interventional Radiology (SIR) and the Cardiovascular and Interventional Radiology Society of Europe (CIRSE).

Michael C. Soulen, Department of Radiology, University of Pennsylvania Hospital, Philadelphia
Michael C. Soulen, MD, received his undergraduate degree from Yale University, Connecticut and his medical degree from the University of Pennsylvania, then trained in radiology at Johns Hopkins University. After clinical and research fellowships in vascular and interventional radiology at Thomas Jefferson University, he started the interventional oncology program at the University of Pennsylvania, where he is currently professor of radiology and surgery. A prolific author and lecturer, Soulen served on the boards of the SIR, SIR Foundation, and the WCIO. He is a Fellow of the SIR and of the CIRSE.
Contributors

Michael C. Soulen, Jean-Francois H. Geschwind, Anthony M. Esparaz, S. Nahum Goldberg, Muneeb Ahmed, Govindarajan Srimathveeravalli, Stephen B. Solomon, Aradhana M. Venkatesan, Bradford J. Wood, Hwan Jun Jae, Jae Hyung Park, Jin Wook Chung, Vanessa L. Gates, Riad Salem, Robert J. Lewandowski, Fidel David Huitzil Melendez, Nancy Kemeny, Francois Cornelis, Kelly Fabrega-Foster, Neda Rastegar, Ihab R. Kamel, Riccardo Lencioni, Laura Crocetti, Maria Clotilde Della Pina, Dania Cioni, Hyo-Cheol Kim, Julius Chapiro, Florian Nima Fleckenstein, Lynn Jeanette Savic, Ryan M. Hickey, Riad Salem, William S. Rilling, Elena N. Petre, Constantinos T. Sofocleous, Govindarajan Narayanan, Ursina Teitelbaum, Lourens Bester, Baerbel Meteling, David Boshell, Terence P. Gade, David Li, David C. Madoff, Vlastimil Valek, Tomas Andrasina, Mansi A. Saksena, Debra A. Gervais, Peter R. Mueller, Ricardo Garcia-Monaco, Erica S. Alexander, Damian E. Dupuy, Matthew R. Callstrom, A. Nicholas Kurup, Sean Tutton, Alexis Kelekis, Jeremy C. Durack, Behfar Ehdaie, J. Coleman, Thierry de Baère, Eric Desruennes, Drew A. Rosielle, Melissa Atwood, Sean Marks, Ashraf Thabet, Hooman Yarmohammadi