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A state-of-the-art, multidisciplinary approach to cancer and aging With the majority of cancers occurring in individuals over the age of 65 against a backdrop of an expanding aging population, there is an urgent need to integrate the areas of clinical oncology and geriatric care. This timely work tackles these issues head-on, presenting a truly multidisciplinary and international perspective on cancer and aging from world-renowned experts in geriatrics, oncology, behavioral science, psychology, gerontology, and public health. Unlike other books on geriatric oncology that focus mainly on treatment, Cancer and Aging Handbook: Research and Practice examines all phases of the cancer care continuum, from prevention through evidence-based diagnosis and treatment to end-of-life care. Detailed clinical and research information helps guide readers on effective patient care as well as caregiver training, research, and intervention. Coverage includes: Epidemiology of cancer in older adults, plus the unique physical, mental, and social issues involved Strategies and guidelines for prevention, screening, and treatment of older individuals with cancer The most common cancers in the elderly, including breast, colorectal, lung, prostate, and ovarian cancer Cancer survival in older adults as well as the all-critical issues of palliative care and pain management Emerging topics such as caregiver and family issues, different models of care, and cost considerations An essential resource for clinicians and caregivers as well as researchers interested in this evolving field, Cancer and Aging Handbook is also useful for public health professionals and policymakers who need to formulate services and allocate resources for the growing population of older cancer patients. CONTENTS PART I CANCER AND AGING IN CONTEXT 1. Epidemiology of Cancer in the Older-Aged Person 3 Lodovico Balducci 2. Biological Aspects of Aging and Cancer 13 Gabriel Tinoco, Mya Thein, and William B. Ershler 3. Physiological, Psychological, and Social Aspects of Aging 35 George A. Kuchel, Julie Robison, and Richard Fortinsky PART II STRATEGIES FOR CANCER PREVENTION IN OLDER ADULTS 4. Overview of Cancer Prevention Strategies in Older Adults 55 Barbara K. Dunn, Peter Greenwald, and Darrell E. Anderson 5. Breast Cancer Prevention 71 Jeanne F. Noe and Hyman B. Muss 6. Colorectal Cancer Prevention and Aging 85 Ernest T. Hawk, Sherri L. Patterson, Lopa Mishra, and Kush K. Patel 7. Prostate Cancer Prevention 97 Barbara Ercole and Ian M. Thompson, Jr. 8. Lung Cancer Prevention 105 Samira Shojaee and Konstantin H. Dragnev PART III CANCER SCREENING GUIDELINES FOR OLDER ADULTS 9. Cancer in Older People: To Screen or Not to Screen? 117 Catherine Terret and Jean-Pierre Droz 10. Breast Cancer Screening 125 Heidi D. Nelson 11. Colorectal Cancer Screening 139 Catherine Quarini 12. Prostate Cancer Screening 153 Anthony B. Miller 13. Other Screening Opportunities for the Future 163 Catherine Quarini PART IV CANCER TREATMENT 14. General Principles in Older Adults with Cancer 175 Martine Extermann 15. Surgery for Older Adults with Cancer 183 Lynda Wyld, Malcolm Walter Ronald Reed, and Thompson Gordon Robinson 16. Chemotherapy in Older Adults with Cancer 205 Matti S. Aapro and Hans Wildiers 17. Radiotherapy in Older Adults with Cancer 221 Ian Kunkler PART V COMMON CANCERS IN THE ELDERLY 18. Breast Cancer 243 Laura Biganzoli, Catherine Oakman, Riccardo A. Audisio, and Ian Kunkler 19. Colon Cancer 269 Demetris Papamichael and Riccardo A. Audisio 20. Lung Cancer 283 Ulrich Wedding 21. Prostate Cancer 315 Nicolas Mottet and Jean-Pierre Droz 22. Ovarian Cancer 335 Claire Falandry, Gilles Freyer, and Eric Pujade-Lauraine PART VI CANCER SURVIVORSHIP AND AGING 23. Theoretical Perspectives from Gerontology and Lifespan Development 349 Thomas O. Blank 24. Adaptation and Adjustment to Cancer in Later Life: A Conceptual Model 365 Gary T. Deimling, Boaz Kahana, and Karen Bowman 25. Long-Term and Late Physical and Psychosocial Effects of Cancer in Older Adults 385 Kerri M. Clough-Gorr and Rebecca A. Silliman PART VII END-OF-LIFE CARE 26. Palliative Care for Cancer Patients and Their Families 403 Cardinale Smith and Diane Meier 27. Pain Management 419 Paul Glare, Beatriz Korc-Grodzicki, Nessa Coyle, and Manpreet Boparai PART VIII EMERGING ISSUES 28. Caregiver Knowledge and Skills 447 Paula R. Sherwood, Barbara A. Given, and Charles W. Given 29. Comprehensive Geriatric Assessment 459 Lazzaro Repetto and Angela Marie Abbatecola 30. Economic Cost of Treating Older Adults with Cancer 475 Ya-Chen Tina Shih and Benjamin D. Smith 31. Multidisciplinary Models of Care 487 Kathleen Tschantz Unroe and Harvey Jay Cohen INDEX 499
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