Epilepsy: Basic Principles and Diagnosis Part I

This is the first of two volumes on Epilepsy in the Handbook of Clinical Neurology series. It deals with the basic principles of the epilepsies and their diagnosis. Hermann Stefan, Director of Epilepsy Centre, Neurological Clinic, University Hospital, Erlangen, Germany and William H. Theodore, Clinical Epilepsy Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, and Uniformed Services University of the Health Sciences, Bethesda, MD, USA Table of Contents: SECTION 1  BASIC MECHANISMS 1. Molecular Basis of Acquired Epileptogenesis - K. Lukasiuk and A. Pitkänen (Warsaw, Poland and Kuopio, Finland)    2. Cellular bases of focal and generalised epilepsies - P.A. Schwartzkroin (Davis, USA) 3. Epilepsy as a dynamic disease of neuronal networks - F.H. Lopes Da Silva, J.A. Gorter and W.J. Wadman (Amsterdam, The Netherlands) 4. Animal models - A. Coppola and S.L. Moshé (Bronx, USA and Naples, Italy) 5. Classification of epilepsies and seizures: historical perspective and future directions - A.T. Berg and H. Cross (Chicago, USA and London, UK) 6. The epidemiology of the epilepsies - A. Neligan, W.A. Hauser and J.W. Sander (London, UK, New York, USA and Heemstede, The Netherlands) 7. Maturation of the human brain and epilepsy - G.L. Holmes, M.D.M. Milh and O. Dulac (Lebanon, USA, Marseille, France and Paris, France) 8. Genetics of idiopathic epilepsies - O.K. Steinlein (Munich, Germany) 9. The genetics of focal epilepsies - J.J. Poza (San Sebastián, Spain) 10. Inflammation and epilepsy - A. Vezzani, S. Balosso and T. Ravizza (Milan, Italy) SECTION 2  DIAGNOSIS 11. Age related epileptic encephalopathies - R. Guerrini and J.M. Pellock (Florence, Italy and Richmond, USA) 12. Epileptic syndromes with focal seizures of childhood and adolescence - T. Loddenkemper, E. Wyllie and E. Hirsch (Cleveland, USA, Boston, USA and Strasbourg, France) 13. Idiopathic generalised epilepsies - A. Kao and P.M. Rao (Washington, USA) 14. Temporal lobe epilepsy - M. Thom and E.H. Bertram (London, UK and Charlottesville, USA) 15. Extratemporal epilepsies - S. Bauer and H.M. Hamer (Marburg, Germany) 16. Reflex epilepsies - P. Wolf and M. Koepp (Dianalund, Denmark and London, UK) 17. Psychogenic nonepileptic seizures - P. Widdess-Walsh, B. Mostacci, P. Tinuper and O. Devinsky (Livingston and New York, USA and Bologna, Italy) 18. Syncope - B.A. Engelsen (Bergen, Norway) 19. Sleep and epilepsy - P. Halász (Budapest, Hungary) 20. Electroencephalography and video-electroencephalography - A. Gil-Nagel and B. Abou-Khalil (Madrid, Spain and Nashville, USA) 21. Magnetoencephalography - H. Stefan, N. Nakasato and A.C. Papanicolaou (Erlangen, Germany; Sendai, Japan and Houston, USA) 22. Structural brain imaging - R. Kälviäinen and Arnd Dörfler (Kuopio, Finland and Erlangen, Germany) 23. Functional MR imaging: focus localisation - G.D. Jackson, R. Badawy and J. Gotman (Heidelberg and Melbourne, Australia and Montreal, Canada) 24. Functional MR: functional mapping - W.D. Gaillard and M.M. Berl (Washington and Bethesda, USA) 25. Magnetic resonance spectroscopy in epilepsy - T. Hammen and R. Kuzniecky (Erlangen, Germany and New York, USA) 26. Epilepsy diagnosis: PET - H.T. Chugani, F. Semah, A. Kumar and W.H. Theodore (Detroit, USA; Lille, France and Bethesda, USA) 27. Per-ictal single photon emission computed tomography: principles and applications in epilepsy evaluation - E.L. So and T.J. O’Brien (Rochester, USA and Melbourne, Australia) 28. Clinical neuropsychology in epilepsy: theoretical and practical issues - C. Helmstaedter and J-A. Witt (Bonn, Germany) 29. Neuropsychiatric complications of epilepsy - D.C. Hesdorffer and A.M. Kanner (New York and Chicago, USA)