Textbook of Palliative Medicine and Supportive Care

This new edition provides the essential clinical guidance both for those embarking upon a career in palliative medicine and for those already established in the field. A team of international experts here distil what every practitioner needs to know into a practical and reliable resource.

Table of Contents
List of contributors

1. The development of hospice and palliative care

Kate Kirk

2. Palliative care as a public health issue

Irene J. Higginson and Massimo Costantini

3. Palliative care as a primary care issue

Scott A. Murray, Sebastien Moine, and Kirsty Boyd

4. The future of palliative medicine

Charles F. Von Gunten and Irene J. Higginson

5. Palliative care and supportive care

Eduardo Bruera

6. Ethics in the practice of palliative care

Nelia Jain and James A. Tulsky

7. Undergraduate education in palliative medicine

Linh My Thi Nguyen

8. Graduate education for nonspecialists

Fiona Rawlinson and Ilora G. Finlay

9. Challenges of research in palliative and supportive medicine

Irene J Higginson

10. The population: who are the subjects in palliative medicine research?

Claudia Bausewein and Fliss E.M. Murtagh

11. Study designs in palliative medicine

Massimo Costantini

12. Outcome measurement in palliative care

Joan M. Teno

13. Ethics in palliative care research

Jonathan Koffman

14. Adoption of palliative care: the engineering of organizational change

Winford E. (Dutch) Holland and Eduardo Bruera

15. Principles of measuring the financial outcomes of specialist palliative care programs

J. Brian Cassel and Thomas J. Smith

16. Population-based needs assessment for patients and those important to them, such as families

Irene J. Higginson and Richard Harding

17. Models of palliative care delivery

Eduardo Bruera and Jessica H. Brown

18. Home palliative care

Heather Grant and Dana Lustbader

19. Palliative care unit

Karen Macmillan, Kelley Fournier, Beth Tupala, and Kim Crowe Mackinnon

20. Multidimensional patient assessment

Marvin Omar Delgado Guay and Alexander Harding

21. Tools for pain and symptom assessment

Victor T. Chang

22. Quality of life assessment in palliative care

Richard Sawatzky and S Robin Cohen

23. Pathophysiology of chronic pain

Sebastiano Mercadante

24. Causes and mechanisms of pain in palliative care patients

Michal Kubiak, Marieberta Vidal, Suresh K. Reddy

25. Opioid analgesics

Geana Paula Kurita, Stein Kaasa, and Per Sjøgren

26. Assessment and management of opioid side effects

Shalini Dalal

27. Adjuvant analgesic medications

Jessica Geiger

28. Alternative routes for systemic opioid delivery

Raffaele Giusti, Monica Bosco, Maurizio Lucchesi, and Carla Ida Ripamonti

29. Interventional pain procedures in palliative care

Po-Yi Paul Su, Ann Cai Shah, and Sarah Gebauer

30. Pain management in pediatrics

Kevin Madden

31. Pain in the older adult

Linh My Thi Nguyen and Michelle Peck

32. Neuropathic pain

Paolo Marchettini, Fabio Formaglio, and Marco Lacerenza

33. Bone cancer pain and skeletal complications

Yoko Tarumi

34. Breakthrough (episodic) pain in cancer patients

Shirley H. Bush

35. Somatic symptoms, symptom clusters, and symptom burden

David V. Nelson and Diane M. Novy

36. Pain in patients with alcohol and drug dependence

Leah Couture, Malisa Dang, and Danielle Noreika

37. Cachexia–anorexia syndrome

Paul Zelensky, Mallika Dammalapati, and Egidio Del Fabbro

38. Nausea/vomiting

Sebastiano Mercadante

39. Constipation

Charu Agrawal, MD, Karina Shih, MD

40. Jaundice

Nathan I. Cherny and Norman Levan

41. Malignant bowel obstruction

Carla I. Ripamonti1, Alexandra M. Easson, and Hans Gerdesh

42. Endoscopic treatment of digestive symptoms

Pasquale Spinelli

43. Mechanism, assessment, and management of fatigue

Sean Hutchinson, Sriram Yennurajalingam

44. Breathlessness

Claudia Bausewein, Sara Booth

45. Other respiratory symptoms (cough, hiccup, and secretions)

Regina M Mackey, Francisco Loaiciga

46. Depression/anxiety

Tatsuo Akechi

47. Delirium

Yesne Alici, William S. Breitbart

48. Sleep disturbances in advanced cancer patients

Delmer A. Montoya and Sriram Yennurajalingam

49. Counseling in palliative care

Sophie A McGilvray and David W Kissane

50. Hope in end-of-life care

Cheryl L. Nekolaichuk

51. Dehydration and rehydration

Robin L. Fainsinger

52. Fever, sweats, and hot flashes

Ahsan Azhar and Shalini Dalal

53. Pruritus

Michael Tang, Katie Taylor, and Andrew Thorns

54. Infections in palliative care

Rudolph M. Navari

55. Pediatric palliative wound care: the unique anatomy and physiology of neonatal skin

Joyce M. Black

56 Mouth care

Flavio Fusco

57. Fistulas

Maurizio Lucchesi, Fabio Fulfaro, Raffaele Giusti, and Carla Ida Ripamonti

58. Assessment and management of lymphedema

Ying Guo and Mark V. Schaverien

59. Hypercalcemia

Kimberson Tanco and Saima Rashid

60. Hemorrhage

Timothy Fuller, Kencee Graves, and Jen-Yu Wei

61. Spinal cord compression

Maitry Patel, Adrian Cozma, Edward Chow, and Srinivas Raman

62. Clinical features and management of superior vena cava syndrome

Álvaro Sanz, María Luisa del Valle, and Carlos Centeno

63. Acute pain and management

Mellar P. Davis

64. Suicide

Daniel C. McFarland, Yesne Alici, and William S. Breitbart

65. Cancer: radiotherapy

Adrian Cozma, Maitry Patel, Edward Chow, and Srinivas Raman

66. Chemotherapy, hormonal therapy, targeted agents, and immunotherapy

David Hui

67. Integrative medicine in supportive and palliative care

Gabriel Lopez, Santhosshi Narayanan, Wenli Liu, and Lorenzo Cohen

68. Neurological diseases

Tobias Walbert and Joel Phillips

69. End-stage congestive heart failure

Sam Straw, Klaus K. Witte, and Mark T. Kearney

70. Geriatric palliative care

Kimberson C. Tanco and Maxine De La Cruz

71. Advanced chronic obstructive pulmonary disease

Daisy J.A. Janssen, Lynn F. Reinke, and J. Randall Curtis

72. Other infectious diseases: malaria, rabies, tuberculosis

Richard Harding, Rene Krause, and Sue Marsden

73. Practical resources for palliative care development in countries with limited resources: an iahpc perspective

Liliana De Lima

74. Prognostic indicators of survival

Morena Shkodra, Augusto T. Caraceni, Marco Malton, and Caterina Modonesi

75. Palliative sedation

Nathan I Cherny AM

76. Staff stress and burnout in palliative care

Aimee E. Anderson and Eduardo Bruera

77. Spiritual care

Marvin Omar Delgado Guay and Alexander Harding

78. Family caregivers and cultural sensitivity

Rony Dev and Ali Haider

79. Bereavement

Victoria H. Raveis

80. Children of palliative care patients

Estela Beale and Sujin Ann-Yi

81. Neutropenic fever

Hiroshi Ishiguro and Harumi Gomi

82. Side effects of radiation therapy

Michael Wang and Elizabeth A Barnes

83. Cardiac and pulmonary toxicities of treatments

Marieberta Vidal

84. Oral complications of cancer therapies

Siri Beier Jensen and Deborah P. Saunders

85. Dermatologic side effects

Jen-Yu Wei and Michael Goodblatt

86. Peripheral neuropathy and neurotoxicity

Sheetal Shroff, Akhil Shivaprasad, and Ivo W. Tremont-Lukats

87. Sex and sexuality

Mary K. Hughes, APRN, CT

88. Managing communication challenges with patients and families

Anthony L. Back

89. Supportive and palliative care for patients with HIV infection

Richard Harding, Elizabeth J. Chuang, and Peter A. Selwyn

90. Implantable cardiac devices

Laura J. Morrison

91. Supportive care for patients with advanced chronic kidney disease

Sara N. Davison

92. Palliative care in the emergency department

Travis DeVader and Tammie Quest

93. Optimal Symptom Management in Hematopoietic Stem Cell Transplantation

Katie N Kanter, Allison Kestenbaum, Thomas W LeBlanc, and Eric J Roeland

94. The end of therapy: building the psychosocial and spiritual bridges to survivorship

Marvin Omar Delgado-Guay

and Paige Farinholt

95. Rehabilitation in the acute and chronic care setting

George J. Francis, Ki Y. Shin

96. Long-term cognitive function

Asao Ogawa

97. Gonadal functions and reproductive health

Koji Kawai, Miyuki Harada, Yutaka Osuga, and Hiroyuki Nishiyama

98. Pulmonary rehabilitation

Ryo Kozu

Index

Eduardo Bruera, MD, FAAHPM is Professor and Chair, Department of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Irene J. Higginson, OBE, BMedSci, BMBS, PhD, FMedSci, FRCP, FFPHM is Professor and Director, Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King's College London, UK

Charles F. von Gunten, MD, PhD is Vice President, Medical Affairs, Hospice and Palliative Medicine, OhioHealth, Columbus, Ohio, USA

Tatsuya Morita, MD is Director, Department of Palliative and Supportive Care, Seirei Mikatahara General Hospital, Hamamatsu, and Adjunct Professor, Kyoto University, Japan