Pulmonary Circulation

'This book is at the vanguard of its type in the field of pulmonary circulation, and it achieves the editors' ambitious goal of providing a balance between scientific review and clinically relevant comprehensive guidelines for the busy practising physician'. - New England Journal of Medicine, from a review of the second edition. Andrew J Peacock - Professor of Medicine, Consultant Respiratory Physician and Director, Scottish Pulmonary Vascular Unit, Regional Heart and Lung Centre,Golden Jubilee National Hospital, Glasgow, UK Robert Naeije - Professor of Physiology and Medicine, and Consultant at the Department of Cardiology of the Erasme Academic Hospital of the Free University of Brussels, Belgium Lewis J Rubin - Emeritus Professor of Medicine and Emeritus Director, Pulmonary Vascular Center at the University of California, San Diego School of Medicine, La Jolla, CA, USA Authoritative, comprehensive and definitive, Pulmonary Circulation builds on the success of its previous two editions by providing practising respiratory physicians with a highly-ordered, unique reference work on the structure, function and pathophysiology of the pulmonary circulation. New for the third edition: # Thoroughly revised with comprehensive coverage from diagnosis and clinical evaluation of pulmonary hypertension, to imaging techniques, disorders and treatment # A new truly global team of expert editors, authors and key opinion leaders provide a wealth of detail on the latest developments and issues # New chapters, such as: paediatrics, critical care, special environments including high altitude and underwater # More quality chapters, authors, illustrations with thorough and thoughtful referencing make this book a contemporary essential reference text Pulmonary Circulation remains an essential resource for pulmonary hypertension specialists and should prove invaluable in all respiratory, cardiac and intensive care units. * The definitive reference work in the field * Now with a third editor for added expertise and includes chapters from a truly global contributor list * Highly illustrated and referenced throughout * Appeals to a broad range of clinicians, including respiratory medicine, cardiology and intensive care specialists Table of Contents: The Function of the Normal Pulmonary Circulation & Right Heart Pulmonary vascular function Right heart function Pathophysiology & Pathology of Pulmonary Vascular Disease Pathology of pulmonary vascular disease Hypoxic pulmonary vasoconstriction and hypertension Pulmonary vascular remodeling & pathobiology of pulmonary hypertension Clinical Assessment of Pulmonary Hypertension: Diagnosis & Management Clinical features Imaging: Echocardiography Imaging: Chest radiography, ventilation/perfusions cintigraphy and computed tomography Imaging: Emerging modalities (MR , PET and others) Exercise testing and pulmonary hypertension: Six minute walk testing and cardiopulmonary exercise testing Blood biomarkers Cardiac catheterisation of patients with pulmonary hypertension An integrated approach to the diagnosis and clinical management of pulmonary hypertension Disorders Associated with Pulmonary Hypertension Classification and clinical features of pulmonary hypertension Idiopathic and heritable pulmonary hypertension: Introduction to pathophysiology & clinical aspects Genetics of pulmonary arterial hypertension Pulmonary hypertension related to appetite suppressants Pulmonary hypertension associated with portal hypertension Pulmonary arterial hypertension related to HIV infection Pulmonary hypertension associated with congenital systemic to pulmonary shunts Hemolysis-associated pulmonary hypertension in sickle cell disease and thalassemia Pulmonary hypertension in pregnancy Drug and Non Drug Treatment of Pulmonary Hypertension Conventional medical therapies: general measures, supportive treatments and calcium channel blockers Prostacyclins: intravenous, subcutaneous, inhaled and oral Inhaled nitric oxide and nitric oxide donors Endothelin receptor antagonists The nitric oxide and cyclic guanosine monophosphate pathway Combination therapy for pulmonary arterial hypertension Stem cell therapy Novel antin-proliferative strategies Surgical Treatment of Pulmonary Hypertension 17.1 Lung transplantation Atrial septostomy and other interventional procedures Pulmonary endarterectomy An integrated approach to the treatment of pulmonary arterial hypertension Pulmonary Hypertension due to Capillary or Post Capillary disease 19.1 Pulmonary hypertension secondary to left heart failure Pulmonary veno-occlusive disease Pulmonary capillary hemangionmatosis Pulmonary Hypertension Associated with Disorders of the Respiratory System and/or Hypoxemia Pulmonary hypertension due to chronic hypoxic lung disease COPD and ILD Pulmonary circulation in obstructive sleep apnea 20.3 An integrated approach to treatment of pulmonary hypertension due to hypoxic lung disease Other Important Causes of Pulmonary Hypertension Schistosomiasis Part 10:Acute and Chronic Pulmonary Thromboembolism, Pulmonary Vascular Tumors and Pulmonary Vasculitis. Diagnosis of acute pulmonary thromboembolism Treatment of acute pulmonary thromboembolism Chronic thromboembolic pulmonary hypertension Pulmonary vascular tumors Pulmonary vasculitis Part 11:Pulmonary Hypertension in Pediatrics Idiopathic pulmonary arterial hypertension in children Part 12:Pulmonary Circulation in Critical Care Effects of mechanical ventilation on the pulmonary circulation Effects of lung injury on the pulmonary circulation Pharmacological management of the pulmonary circulation in critically ill patients Pulmonary Circulation in Special Environments High altitude pulmonary hypertension High altitude pulmonary oedema Pulmonary circulation in the underwater environment Disorders Causing Intrapulmonary Shunt Hepatopulmonary syndrome Pulmonary arteriovenous malformations