Did you know that high levels of toxins in the human body can be linked to common conditions such as infertility, obesity, rheumatoid arthritis, heart disease, and diabetes? With therapeutic guidance designed for clinicians, Clinical Environmental Medicine focuses on how toxins such as arsenic, lead, mercury and organophosphates have become one of the leading causes of chronic disease in the industrial world. The first edition of this text describes how to treat these undesirable elements and molecules that can poison enzyme systems, damage DNA, increase inflammation and oxidative stress, and damage cell membranes. Expert authors Walter Crinnion and Joseph E. Pizzorno offer practical guidance for assessing both total body load as well as specific toxins. In addition, evidence-based treatment procedures provide recommendations for decreasing toxin exposure and supporting the body’s biotransformation and excretion processes.
New to this edition
NEW! Unique! Practical diagnostic and therapeutic guidance designed for clinicians.
NEW! Unique! Coverage of the most common diseases for which toxins are a primary cause.
NEW! Description of how each toxin causes damage provides insights into sources, body load, and interventions for each toxin.
NEW! Unique! Entirely evidence-based content focuses on the most common conditions from which patients suffer.
NEW! Unique! Coverage of environmental toxicants, endogenous toxicants, and "toxins of choice" focuses on non-industrially-exposed populations.
Table of Contents:
Section I: Introduction to Environmental Medicine
1. The Science of Environmental Medicine
2. Oxidative Damage and Inflammation
3. Food Pollution
4. Water Pollution
5. Indoor Air Pollution
6. Outdoor Air Pollution
7. Health and Beauty Products
Section II: The Toxicants
11. Hexavalent Chromium
15. Other Metals
17. Benzene, Toluene, Ethylbenzene, Xylenes (BTEX)
18. Chlorinated Solvents
20. Organochlorine Pesticides
21. Organophosphate Pesticides
22. Pyrethroid Pesticides
23. Glyphosate and Petroleum Distallates
24. Chlorophenoxy Herbicides
25. Bisphenol A
27. Polybrominated Diphenyl Ethers
28. Polychlorinated Biphenyls
30. Parabens and Other Preservatives
31. Mold and Water-Damaged Building Toxicity
33. Particulate Matter and Polycyclic Aromatic Hydrocarbons
34. Sulfur and Nitrogen Oxides
Toxins of Choice
38. High Fructose Corn Syrup
Section III: Systemic Effects of Toxins
44. Endocrine Toxicity
45. Mitochondrial Toxicity
46. Respiratory Toxicity
47. Cardiovascular Toxicity
48. Musculoskeletal Toxicity
49. Liver Toxicity
50. Renal Toxicity
Section IV: Assessment of Toxic Load
53. Laboratory Assessment of Toxicant Levels
54. Conventional Laboratory Tests to Assess Toxic Load
55. 8-Hydroxy-2'-deoxyguanosine and Other Nucleoside Metabolites
Section V: Biotransformation and Excretion
56. Normal Biotransformation
57. Lung Excretion
58. Hair Excretion
59. Breast Milk Excretion
Section VI: Therapeutics
62. Gastrointestinal and Renal Elimination
64. Chelation (Oral and IV)
65. Nutritional Supplementation for Environmental Toxins and Toxicants
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