Sjogren's Syndrome

Primary Sjögren's syndrome is a rheumatic disease affecting around 0.1-0.2% of the adult female population and can result in significant disability without adequate therapy. Diagnosis is often delayed and suggested therapies may not be optimal, and a multidisciplinary approach that includes rheumatologists, ophthalmologists, oral medicine physicians, and others is important to patient management.
This volume summarises current understanding of the pathogenesis of the disease, including advances in the genetics of Sjögren's syndrome. Chapters cover disease mechanisms, clinical diagnosis and assessment, secondary Sjögren's syndrome, the role of laboratory investigations, and imaging. A therapy-based section covers topical oral and ocular therapies, and the role of steroids and biologics are also addressed.
Sjögren's Syndrome is a practical concise pocketbook featuring key points and illustrations showing important mechanisms of disease and pathways of care. The book will be of interest to trainees in rheumatology, ophthalmology, and oral medicine/surgery; specialist practitioners and therapists involved in the care of patients with Sjögren's syndrome; and primary care physicians, dentists, and other specialists such as ENT physicians.

Table of Contents

1: Epidemiology, genetics, and disease burden, Simon Bowman
2: Diagnosis and clinical assessment, Wan-Fai Ng, Rebecca Batten, and Imna Rahiman
3: Oral features, Arjan Vissink, Frederik KL Spijkervet, and Hendrika Bootsma
4: Ocular features, Saaeha Rauz
5: Fatigue, pain, and quality of life, Roald Omdal and Katrine Norheim
6: Systemic features (extra-glandular) features, Elizabeth Price
7: Evidence-based evaluation and therapies, Raphaäl eeror and Divi Cornec
8: Lymphoma: Pathogenesis, prediction, and therapy, Francesca Barone and Serena Colafrancesco
9: Case Studies, Benjamin Fisher

Edited by Wan-Fai Ng, Musculoskeletal Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, UK

Wan-Fai Ng is a Professor of Rheumatology at Newcastle University and an Honorary Consultant Rheumatologist at Newcastle upon Tyne Hospital NHS Foundation Trust. He is also the co-director of Arthritis Research UK Newcastle Biomedicine Experimental Arthritis Treatment Centre.

Contributors:

Francesca Barone, University of Birmingham, UK
Rebecca Batten, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK
Hendrika Bootsma, University Medical Center Groningen, The Netherlands
Simon Bowman, Queen Elizabeth Hospital, Birmingham, UK
Serena Colafrancesco, Sapienza University of Rome, Italy
Divi Cornec, Université de Brest, Brest, France
Benjamin Fisher, University of Birmingham, UK
Katrine BrÃkke Norheim, Stavanger University Hospital, Norway
Roald Omdal, Stavanger University Hospital, Norway
Elizabeth Price, Great Western Hospital, Swindon, UK
Imna Rahiman, Musculoskeletal Research Group, Newcastle University, UK
Saaeha Rauz , University of Birmingham, UK
Raphaäe Seror, Université Paris-René Descartes, France
Frederik KL Spijkervet, University Medical Center Groningen, The Netherlands
Arjan Vissink, University Medical Center Groningen, The Netherlands