Primary Immunodeficiency Diseases

A Molecular and Cellular Approach

C. I. Edvard Smith Jennifer M. Puck Hans D. Ochs

Klinische immunologie, Pediatrie - Allergologie, immunologie, Geboorte defecten, erfelijke ziekten

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Inhoud

Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options - from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy - this volume will remain an authoritative resource on this increasingly important area.

Specificaties

Uitgeverij: Oxford University Press Inc
Publicatiedatum: 10 maart 2014
Pagina's: 936
ISBN: 9780195389838
Editie: 3
Uitvoering: Hardback

Over de auteur

Hans D. Ochs, MD, Dr.med, is Professor of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, WA. C. I. Edvard Smith, MD, PhD, is Professor of Molecular Genetics, Karolinska Institutet, Stockholm, Sweden. Jennifer M. Puck, MD, is Professor of Pediatrics and Medical Director of the Pediatric Clinical Research Center, University of California, San Francisco.

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