Mayo Clinic Antimicrobial Therapy

The medical management of infectious diseases and antimicrobial therapy can be a daunting task for health care professionals. Infectious diseases experts at Mayo Clinic provide a coordinated, unified approach to infectious disease treatment for the general patient population as well as the complex patients seen at this internationally renowned destination medical center. Over twenty contributors represent the spectrum of infectious disease experience within the Mayo Clinic framework of patient-centered care. Highlights of Mayo Clinic Antimicrobial Therapy: Quick Guide, Third Edition include simplified and thorough drug dosing recommendations for renal function and renal replacement therapies, drugs of choice for specific organisms (including bacteria, fungi, and viruses), and updated and simplified antimicrobial and management recommendations for specific infectious syndromes. New features of the third edition include dosing recommendations for extended infusions and obese and neonatal patient populations and treatment options targeted for hepatitis B and C infections, prosthetic joint infections, post-transplant infections, and infections resulting from bioterrorism. This compact, user-friendly resource brings the specialized knowledge of Mayo Clinic to your fingertips.

Contents
Section I. Antimicrobial Dosing-Adult
Adult Antimicrobial Dosing
Adult Antimicrobial Dosing With Obesity
Extended Infusions
Adult Dosing for Continuous Renal Replacement Therapy in Patients with Minimal Residual Renal Function
Vancomycin Adult Dosing and Monitoring Guidelines
Aminoglycoside Adult Dosing and Monitoring
Section II. Antimicrobial Dosing-Pediatric
Pediatric Antimicrobial Dosing
Neonatal Dosing
Pediatric Vancomycin Dosing
Pediatric Aminoglycoside Dosing
Section III. Antimicrobial Agent Fundamentals
Pharmacokinetics of Antimicrobial Agents
Antimicrobial Drug Levels
Laboratory and Clinical Toxicity Monitoring
Section IV. Treatment of Specific Organisms
Spectrum of Activity
Bacteria: Preferred and Alternative Treatment Options
Bacterial Drug Resistance
Fungi: Preferred and Alternative Treatment Options
Viruses: Preferred and Alternative Treatment Options
Section V. Infectious Syndromes in Adults
Clinical Approach to Patients With Infection
Respiratory Tract Infections
Infective Endocarditis: Diagnosis and Treatment
Infective Endocarditis: Prophylaxis
Intravascular Catheter-Related Infections
Central Nervous System Infections
Urinary Tract Infections
Soft Tissue Infections: Nontoxigenic
Soft Tissue Infections: Necrotizing or Toxigenic
Osteomyelitis
Native Joint Infection
Prosthetic Joint Infection
Gastrointestinal Infections
Intra-abdominal Infections
Management of the Febrile Neutropenic Patient
Transplant Infections
Sexually Transmitted Diseases
Tuberculosis
Nontuberculosis Mycobacteria Management Pearls
Fungal Infections
Hepatitis B
Chronic Hepatitis C Infection
Antiretroviral Therapy for HIV-1 Infection
Select Opportunistic Infections in Adult Patients With HIV
Occupational and Nonoccupational HIV, HBV, and HCV Postexposure Prophylaxis and Management
Tick-borne Infections
Zoonotic (Animal-Associated) Infections
Vaccination Schedules
Travel Medicine and Prophylaxis
Bioterrorism

John W. Wilson, MD is a consultant for the Division of Infectious Diseases, Department of Internal Medicine and Associate Professor at Mayo Clinic College of Medicine and Science. Lynn L. Estes, PharmD is a Infectious Disease Pharmacy, Associate for the Division of Infectious Diseases, Department of Internal Medicine and Assistant Professor of Pharmacy at Mayo Clinic College of Medicine and Science.