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Written by a multidisciplinary team of internationally recognized authors, this book delivers an in-depth and practical overview of peripheral arterial disease. It covers all major extracardiac arterial systems and serves as a point-of-care reference for the vascular surgeon, radiologist, vascular internist, and cardiologist. Peripheral Arterial Disease offers essential insights on clinical presentation, diagnostic tests, and various treatment options, including medical, surgical, and endovascular modalities. Expert coverage of anatomy, epidemiology, risk factors, pathophysiology, and more Focus on both common and rare disease states in all peripheral circulations Section on diagnostic imaging modalities, including agiography, IVUS, MRI, and ultrasound Over 500 color figures, tables, and charts Author team represents a wide range of specialties Important chapters on vasculitis, intracranial disease, carotid artery disease, the ascending thoracic aorta, and lower extremity peripheral arterial disease-all of which reflect the book's expansive scope Review of fundamental topics such as clinical assessment of endothelial function, blood pressure regulation, taking patient history and the physical exam CONTENTS 1 The Epidemiology of Peripheral Arterial Disease 2 Gender Differences in the Epidemiology and Management of Vascular Disease 3 Lipids in the Pathogenesis of Peripheral Arterial Disease 4 Vulnerable Plaque and the Role of Inflammation in Vascular Disease 5 The Endothelium in Health and Disease 6 Clinical Assessment of Endothelial Function 7 Flow Dynamics and Arterial Physiology 8 Blood Pressure Regulation 9 Hypertension 10 Hypercoagulability and Peripheral Arterial Disease 11 Infections of the Peripheral Arterial System 12 Overlap of Atherosclerotic Disease 13 Coronary Artery Disease in Patients with Peripheral Arterial Disease 14 Vasculitis 15 Connective Tissue Disorders in Peripheral Vascular Disease 16 History and Physical Examination 17 Noninvasive Vascular Imaging 18 Magnetic Resonance Imaging 19 CT Angiography 20 Peripheral Angiography 21 Intravascular Ultrasound in Peripheral Arterial Disease 22 Intracranial Arterial Disease 23 Extracranial Carotid Disease 24 Vertebrobasilar Disease 25 Ascending Aorta 26 The Ascending Thoracic Aorta and Aortic Arch 27 Aortic Arch Vessels and Upper Extremity Arteries 28 Descending Thoracic Aorta 29 Abdominal Aorta 30 Mesenteric Artery Disease 31 Renal Artery Disease 32 Lower Extremity Peripheral Arterial Disease 33 Medical Therapy of Intermittent Claudication 34 Approach to the Patient with Chronic Critical Limb Ischemia of the Lower Extremities 35 Acute Limb Ischemia 36 Lower Extremity Revascularization for Atherosclerotic Occlusive Disease 37 Endovascular Therapies in Peripheral Arterial Disease 38 The Vascular Biology and Clinical Efficacy of Drug Eluting Stents for the Treatment of Peripheral Arterial Disease 39 Gene Therapy for Peripheral Arterial Disease 40 Peripheral Vascular Brachytherapy 41 Diabetic Peripheral Disease 42 Wound Care 43 Erectile Dysfunction 44 Embolic Disorders of the Pulmonary Artery 45 Nonembolic Disorders of the Pulmonary Artery 46 Steal Syndromes 47 Hemodialysis Access 48 Vascular Trauma 49 Primary Vascular Tumors 50 Contemporary Treatment of Congenital Vascular Malformations 51 Arterial Complications in Transplantation 52 Perioperative stroke