The Daschner Guide to In-hospital Antibiotic Therapy

* Handy - concise - clear * The "always on-hand" pocket guide to the treatment of infectuous diseases * The most important antibiotics and antimycotics: Spectrum - dosage - side-effects * Numerous tables sorted by substances, pathogens, indications * Administration of antibiotics during pregnancy, renal and hepatic insufficiency, dialysis * Including statements on the cost of therapy Numerous tips and troubleshooting guides on topics such as: - Potential mistakes - Therapy failures - Perioperative antibiotic prophylaxis Adjusted to European standards: Up-to-date substances, authorizations, resistances and trade names. The first guide to antibiotic therapy for Europe! All in all, an approach that looks towards the future in which antimicrobial resistance will certainly represent an ever-growing obstacle for the medical class, and for which books like this will undoubtedly represent a precious resource. - Giuseppe Cornaglia, MD, PhD, President, European Society of Clinical Microbiology and Infectious Diseases (ESCMID) This book will most certainly be a valuable asset for all those treating patients with infections. While primarily aimed at the hospital setting, most of the very useful information can certainly be used in other healthcare settings, too. - Andreas Voss, Professor of Clinical Microbiology and Infection Control Radboud University Nijmegen Medical Centre and Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands Uwe Frank, MD, PhD Professor of Clinical Microbiology Department of Environmental Health Sciences at the Freiburg University Medical Center Evelina Tacconelli, MD, PhD Assistant Professor of Infectious Diseases Institute of Infectious Diseases at the Università Cattolica del Sacro Cuore, Rome, Italy Contents 1 Classification of the Antibiotics . . . . . . . . . . . 1 2 Antibiotics Marketed in the EU . . . . . . . . . . . 5 3 Principles of Antibiotic Therapy . . . . . . . . . . . 37 4 The Most Common Errors in Antibiotic Therapy . . 41 5 Important Infections and Their Microbiological Diagnosis . . . . . . . . . . . . . . . . . . . . . . 44 6 Cooperation with Microbiologists . . . . . . . . . . 46 7 Resistance of Major Clinical Pathogens . . . . . . 48 8 The Most Frequent Pathogens – Choice of Antibiotics . . . . . . . . . . . . . . . . . . . . . . 71 9 Antibiotics, Antimycotics: Spectrum – Dosage – Adverse Effects – Costs . . . . . . . . . . . . . . 77 10 Antibiotic Therapy of the Principal Infections in Children and Adults . . . . . . . . . . . . . . . 176 11 Treatment of the Most Frequent Types of Bacterial Endocarditis . . . . . . . . . . . . . . . . . . . . . 231 12 Minimal Duration of Treatment for Bacterial Infections . . . . . . . . . . . . . . . . . . . . . . 235 13 Failure of Antibiotic Therapy . . . . . . . . . . . . 237 14 Fever of Unknown Origin: Differential Diagnosis . . 238 15 Dosage of Antibiotics in Impaired Renal Function . 246 16 Antibiotic Therapy in Haemodialysis, Peritoneal Dialysis, and Continuous Haemofiltration . . . . . . 250 17 Antibiotic Therapy During Pregnancy and Lactation 267 18 Antibiotics in Liver Diseases . . . . . . . . . . . . 269 19 Diffusion of Antibiotics in Cerebrospinal Fluid and in Cerebral Abscesses . . . . . . . . . . . . . 271 20 Local Antibiotics . . . . . . . . . . . . . . . . . . 273 21 Prophylactic Antibiotic Therapy . . . . . . . . . . . 275 22 Physical Incompatibility of Antibiotics and Antimycotics in Infusion Solutions . . . . . . . 292 23 Useful Websites . . . . . . . . . . . . . . . . . . . 295