Head and Neck Pathology

The head and neck is the site of some of the most diverse and histologically complex tumors in the human body. Within this small, highly specialized region, one finds a remarkable range of tissues, including skin, mucosal surfaces, soft tissue, bone, lymph nodes, peripheral and central nervous system tissue, paraganglia, endocrine organs, salivary glands and odontogenic structures. Compounding the issue, biopsies are often small, frequently distorted and difficult to orient for paraffin embedding, all of which impact evaluation and diagnosis, even for experienced pathologists. Head and Neck Pathology presents fifty cases for discussion and illustration. The cases have been selected to show the wide range of specimens seen in head and neck pathology and address some of the frequent encountered in these lesions. The goal of this unique book is to provide detailed insight into a wealth of expert experience in such cases, with in-depth review of the expert's analysis and diagnostic process supported by high-quality color photomicrographs and discussion of the diagnostic principles involved in evaluating these lesions. Head and Neck Pathology is essential reading for surgical pathologists, otolaryngologists and pathologists. In addition it will of interest to pathology and otolaryngology residents and fellows. About the Series: The Consultant Pathology series is designed to disseminate the knowledge of expert surgical pathology consultants in the analysis and diagnosis of difficult cases to the full community of pathology practitioners. The volumes are based on actual consultations and presented in a format that illustrates the expert's process of evaluating the case, including indications for consultation, the consultant's findings and comment, and discussion of the entity that amplifies the case description. Each volume in the Consultant Pathology series is authored by international experts with extensive case experience in the areas covered. Contents Series Foreword; Preface; Acknowledgements; 1. Squamous Cell Carcinoma - Variants: 1.1 Adenosquamous Carcinoa, 1.2 Basaloid squamous cell carcinoma, 1.3 hybrid verucous carcinoma, 1.4 Spindle cell squamous carcinoma, 1.5 Verrucous carcinoma - papillary keratosis; 2. Salivary Glands: 2.1 Acinic cell carcinoma, 2.2 Adenoid cyst carcinoma with high-grade transformation, 2.3 Chronic sclerosing sialadenitis (Kuttner tumor), 2.4 Epithelial - myoepithelial carcinoma, 2.5 Keratocystoma, 2.6 Low-grade salivery duct carcinoma (low-grade cribiform cystadenocarcinoma), 2.7 Oncocytic mucoepidermoid carcinoma, 2.8 polymorphous low-grade adenocarcinoma, 2.9 Salivary duct carcinoma, 2.10 Salivary gland sebaceous carcinoma, 2.11 Sclerosing polycystic adenosis, 2.12 Sialadenoma papilliferum; 3. Sinonasal Tract- Nasopharynx: 3.1 Exophytic schneiderian papilloma, 3.2 Nasophatyngeal carcinoma, 3.3 respiratory epithelial adenomatoid hamartoma - inverted papilloma; 4. Dental Lesions: 4.1 Calcifying cystic adontogenic tumor, 4.2 Calcifying epithelial odontogenic tumor (Pindborg Tumor), 4.3 Dental follicle - dental papilla - myxoma, 4.4 Glandular odontogenic cyst, 4.5 Keratocystic odontogenic tumor (odontogenic keratocyst); 5. Neural - Neuroctodermal Lesions: 5.1 Craniopharyngioma, 5.2 Malignant peripheral nerve sheath tumor, 5.3 Middle ear adenoma - paraganglioma - otitis media with glandular metaplasia, 5.4 Mixed olfactory neuroplastoma - carcinoma, 5.5 Mucosal melanoma, 5.6 Secretory Meningioma; 6. Soft Tissue Tumors: 6.1 angiosarcoma, 6.2 Glomangiopericytoma - solitary fibrous tumor, 6.3 Inflammatory myofibroblastic tumor, 6.4 Lobular capillary hemangioma, 6.5 Synovial sarcoma; 7. Bone Tumors: 7.1 Cnetral giant cell granuloma, 7.2 Chordoma, 7.3 Ossifying fibroma (conventional type); 8. Endocrine Tumors: 8.1 Carcinoma metastatic to thyroid, 8.2 Mixed medullary - papillary thyroid carcinoma, 8.3 Paraganglioma of thyroid, 8.4 parathyroid adenoma; 9. Miscellaneous Lesions: 9.1 Branchial cleft cyst - carcinoma 9.2 Eosinophilic angiocentric fibrosis, 9.3 Follicular dendritic cell sarcoma, 9.4 histoplasmosis, 9.5 Median rhomboid glossitis, 9.6 Rosai - Dorfman disease - rhinoscleroma, 9.7 Wegner's granulomatosis About the Authors Leon Barnes, MD is Professor of Pathology and Otolaryngology, University of Pittsburgh School of Medicine and Chief, Division of Head and Neck Pathology, University of Pittsburgh Medical Center; Raja Seethala, MD, Assistant Professor of Pathology, University of Pittsburgh School of Medicine. Simion I. Choisea, MD, Assistant Professor of Pathology, University of Pittsburgh School of Medicine. David E. Elder, MB, ChB, is Professor of Pathology and Laboratory Medicine and Vice Chair for Anatomic Pathology at the Hospital of the University of Pennsylvania.