Clinical Biochemistry Lecture Notes presents the fundamental science behind common biochemical investigations used in clinical practice. Taking a system-based approach, it explores the underlying physiological rationale for tests, with each test explained within the context of disruption by disease. It also explores the value and limitations of biochemical investigations, while helping readers to quickly develop the knowledge and skills required to select the appropriate investigations for diagnosis and management, and to correctly interpret test results. Case studies throughout chapters place the information within a clinical context to further assist readers in the development of test-selection and interpretation skills.
Key features include:
A comprehensive, yet concise overview of the science behind common biochemical investigations
Helps readers rapidly acquire a fully integrated, practical understanding of biochemical diagnostics
Full-colour flowcharts and algorithms detailing the rationale for tests, the biochemical processes involved, and test procedures, for quick comprehension and reference
More clinical cases demonstrating application to practice
Now in its tenth edition, this classic introductory, reference, and revision text is indispensable to medical students, and all those who want to quickly acquire a practical understanding of the scientific principles underpinning biochemical tests and a working knowledge of test selection, test procedures, and the interpretation of results within a clinical context.
Contents
Preface
List of abbreviations
About the companion website
Chapter 1 Requesting and interpreting tests
Chapter 2 Disturbances of water, sodium and potassium balance
Chapter 3 Acid–base balance and oxygen transport
Chapter 4 Renal disease
Chapter 5 Disorders of calcium, phosphate and magnesium metabolism
Chapter 6 Diabetes mellitus and hypoglycaemia
Chapter 7 Disorders of the hypothalamus and pituitary
Chapter 8 Abnormalities of thyroid function
Chapter 9 Disorders of the adrenal cortex and medulla
Chapter 10 Investigation of gonadal function infertility, menstrual irregularities and hirsutism
Chapter 11 Pregnancy and antenatal screening
Chapter 12 Cardiovascular disorders
Chapter 13 Liver disease
Chapter 14 Gastrointestinal tract disease
Chapter 15 Nutrition
Chapter 16 Trauma, inflammation and immunity
Chapter 17 Malignancy and tumour markers
Chapter 18 Disorders of iron and porphyrin metabolism
Chapter 19 Uric acid, gout and purine metabolism
Chapter 20 Central nervous system and cerebrospinal fluid
Chapter 21 Therapeutic drug monitoring and chemical toxicology
Chapter 22 Clinical biochemistry in paediatrics and the elderly
Index
Peter Rae is Consultant Clinical Biochemist at the Royal Infirmary of Edinburgh, and Honorary Senior Lecturer, University of Edinburgh, UK.
Mike Crane is Consultant Clinical Scientist at the Royal Infirmary of Edinburgh and Royal Hospital for Sick Children, and Honorary Lecturer, University of Edinburgh, UK.
Rebecca Pattenden is Consultant Clinical Scientist at Western General Hospital, Edinburgh, UK.
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