Pathology of the Prostate

Prostate cancer is the most commonly diagnosed noncutaneous neoplasm in men in the United States and is the second leading cause of cancer mortality. It poses diagnostic challenges in day-to-day practice in misdiagnosis of tumor-like lesions and secondary tumors. This book is a concise, practical guide to prostate pathology and is structured to guide pathologists, both practicing and trainees, in the diagnostic process. Numerous color images and algorithms show, in a practical manner, how to integrate pathologic and immunohistochemical features to reach a correct diagnosis in prostate tumors and tumor-like lesions. The book incorporates recent developments in biomarkers applied to immunohistochemistry, representing the best immunohistochemistry practice applied to current diagnosis of prostate cancer in biopsies and surgical specimens. It takes a multidisciplinary approach to the clinical management of prostate cancer and will also appeal to all healthcare professionals treating patients, particularly urologists, oncologists, biomedical scientists, and researchers. This book provides access to an online version on Cambridge Core, accessed via the code printed on the inside of the cover.

    A concise, practical, algorithmic guide to prostate pathology based on representative images, practical immunohistochemistry and clinical details of each entity
    Takes a structured multidisciplinary approach to guide pathologists, both practicing and trainees, in the diagnostic process and will also appeal to all healthcare professionals treating patients, particularly urologists, oncologists, biomedical scientists and researchers
    Packaged with a password to give the user online access to an HTML version of the text on Cambridge Core with fully searchable text, expandable tables and figures, and diagnostic algorithms

Table of Contents

1. Basic anatomy and histology of the prostate
2. Inflammatory and tumor-like conditions of the prostate
3. Preneoplastic lesions and conditions of the prostate
4. Adenocarcinoma of the prostate
5. Gleason grading of prostate cancer
6. Histologic subtypes of prostatic carcinoma
7. Neuroendocrine tumors of the prostate
8. Pathologic prognostic factors of prostate cancer
9. Pathology of the prostate after treatment
10. Basic molecular pathology of prostate cancer
11. Rare forms of prostatic carcinoma
12. Tumors and tumor-like conditions of the prostate stroma
13. Soft tissue and miscellaneous primary tumours of the prostate
14. Metastatic and secondary tumors of the prostate
15. The seminal vesicles and ejaculatory ducts
16. Pathology of the prostatic urethra
17. Practical immunohistochemistry of prostate cancer and related lesions

Antonio Lopez-Beltran is Professor of Anatomic Pathology at Córdoba University Medical School and Director of Anatomic Pathology at Champaplimaud Clinical Center. He is also Chairman of the European Working Group on Urologic Pathology and a member of the World Health Organization Expert Panel on Urologic tumors along with Professor Cheng, Professor Monritoni, and Dr Raspollini.

Liang Cheng is Professor of Pathology and Urology at the Indiana University School of Medicine where he is also Chief of the Genitourinary Pathology Service, Director of the Urologic Pathology Fellowship, and Director of Molecular Diagnostics and Molecular Pathology Laboratories.

Rodolfo Montironi is Professor of Pathology at the University of Ancona and Head of the Genitourinary Cancer Program at the Institute of Pathological Anatomy and Histopathology, Polytechnic University of the Marche Region (Ancona) School of Medicine, United Hospitals. He is also Chairman of the ESUP, a full section of the European Association of Urology devoted to Urologic Pathology.

Maria Rosaria Raspollini is consultant pathologist at the University Hospital Careggi, Florence, with expertise in gynaecological and urological pathology and in the application of molecular techniques in uropathology.