Neuropsychiatric and Cognitive Changes in Parkinson's Disease and Related Movement Disorders

Psychiatric and cognitive changes are common in patients with Parkinson's disease and have key clinical consequences but, despite this, these symptoms are often under-diagnosed and under-treated, leading to increased morbidity and costs. With chapters focused on the major neuropsychiatric features, Neuropsychiatric and Cognitive Changes in Parkinson's Disease and Related Movement Disorders rectifies this deficit. Written by experts in the field, with a consistent focus on relevant clinical knowledge, it provides a comprehensive overview including all the major behavioral changes associated with movement disorders. The book provides broad, in-depth, accurate and up-to-date scientific information as well as crucial understanding and practical tools to help patients. The book is essential reading for clinicians working in neurology, psychiatry and geriatric medicine. Table of Contents Preface; Part I. General Aspects: 1. Overview of Parkinson's disease: epidemiology, diagnosis, course, medical and surgical management Sheila S. Rane and Christopher G. Goetz; 2. Parkinson's disease: pathology, anatomy, and behavior James B. Leverenz and Daniel J. Burdick; 3. Genetics and behavior and cognition in Parkinson's disease Caroline H. Williams-Gray and Roger A. Barker; 4. The boundaries of Parkinson's disease dementia and dementia with Lewy bodies Elisabet Londos; Part II. Diagnosis and Biomarkers: 5. Cognitive assessment in Parkinson's disease Jaime Kulisevsky, Saül Martínez-Horta and Javier Pagonabarraga; 6. Clinical assessment: mood and motivation Albert F. G. Leentjens; 7. Imaging and behavior in Parkinson's disease: structural imaging Mona K. Beyer, Turi O. Dalaker and Liana G. Apostolova; 8. Imaging and behavior in Parkinson's disease: functional imaging Agneta Nordberg; 9. Diagnosis and biomarkers: CSF Brit Mollenhauer and Henrik Zetterberg; Part III. Specific Neuropsychiatric Disorders: 10. Depression Per Svenningsson and Dag Aarsland; 11. Anxiety Laura Marsh and Jessica Calleo; 12. Apathy Kathy Dujardin; 13. Impulse control disorder Daniel Weintraub and Irena Rektorova; 14. Hallucinations and psychosis Oscar Bernal-Pacheco and Hubert H. Fernandez; 15. Early cognitive impairment Alexander I. Tröster and Dag Aarsland; 16. Parkinson's disease dementia: features and management Başar Bilgiç, Haşmet A. Hanağasi and Murat Emre; 17. Sleep disturbances Pouya Movahed, Kristina Røkenes Karlsen and K. Ray Chaudhuri; Part IV. Management: 18. Parkinson's disease: drug treatment and behavior Jaime Kulisevsky, Javier Pagonabarraga and Carolina Villa-Bonomo; 19. Surgical treatments and behavior Jens Volkmann and Christine Daniels; 20. Clinical trials for psychotropic agents in Parkinson's diesase using psychosis as a model Ryan R. Walsh and Jeffrey Cummings; Part V. Other Issues: 21. Clinical implications of neuropsychiatric symptoms in Parkinson's disease Angelo Antonini and Pablo Martinez-Martin; 22. Neuropsychiatric and cognitive disorders in other Parkinsonian disorders Adam Gerstenecker, Benjamin T. Mast and Irene Litvan; 23. Neuropsychiatric aspects of the on-off phenomenon Irene Rektorova and Marek Balaz; 24. Treatment of neuropsychiatric disturbances in Parkinson's disease: future prospects and strategies Jeffery Cummings and Dag Aarsland; Index.