Fertility Preservation in Male Cancer Patients

Men with cancer rendered infertile by surgery, chemotherapy, radiation and hormone therapy that are needed to control or cure their disease are increasingly being offered the chance to preserve their reproductive potential through artificial reproductive technologies. Cryopreservation of sperm and testicular tissue have increasingly helped boys and men preserve their fertility. There is a growing subspecialty within reproductive medicine aimed at fertility preservation in this population. Furthermore, strategies are being developed that may in the future revolutionize the approach to such patients. Written by international authorities in the field of fertility preservation, this comprehensive book is aimed at clinicians dealing with male cancer patients, in particular, urologists, andrologists, oncologists, pediatricians, nursing staff as well as clinicians in reproductive endocrinology. The text reviews the impact of cancers and their treatment on male fertility, the available fertility preservation strategies and post-treatment management. Features • Practical commentaries aid in delivering effective patient care • State-of-the-art information is presented in a reader-friendly manner • Resources are clearly listed enabling easy access to further information   Table of Contents Preface Part I. Anatomy and Physiology: 1. Functional anatomy of the hypothalamic-pituitary-testis axis and male reproductive tract Nelson E. Bennett, Jr 2. Spermatogenesis Kathleen Hwang, Alex Ridgeway and Dolores J. Lamb 3. The semen analysis Mary K. Samplaski and Edmund S. Sabanegh, Jr 4. Physiology of ejaculation François Giuliano and Pierre Clément Part II. Disorders of Male Fertility: 5. History and physical examination Ndidiamaka Onwubalili and Hossein Sadeghi-Nejad 6. Abnormalities of semen parameters Daniel H. Williams IV and Jay I. Sandlow 7. Azoospermia Cara B. Cimmino and Robert D. Oates 8. Varicocele Peter J. Stahl and Marc Goldstein 9. Disorders of ejaculation Doron S. Stember and John P. Mulhall 10. Androgen deficiency in the male Gregory C. Mitchell and Wayne J. G. Hellstrom 11. Infertility and male sexual dysfunction Raanan Tal Part III. Impact of Cancers and Treatment of Male Fertility: 12. Radiation effects on spermatogenesis Fabio Firmbach Pasqualatto and Ashok Agarwal 13. Chemotherapy: effects on spermatogenesis Akanksha Mehta and Mark Sigman 14. Effects of therapy for solid tumors Gretchen A. Gignac and Leonard H. Wexler 15. Lymphoma and leukemia Eytan Stein and Ariella Noy 16. Stem cell transplantation Ann A. Jakubowski 17. Fertility preservation in men with germ cell tumors Matthew T. Roberts and Keith Jarvi 18. Effects of therapy for brain cancer Elena Pentsova and Andrew B. Lassman 19. Male infertility following childhood cancer: special considerations for fertility preservation in children Mark F. H. Brougham and W. Hamish B. Wallace Part IV. Preservation Strategies: 20. Facilitating discussion about fertility preservation Gwendolyn P. Quinn and Susan T. Vadaparampil 21. Development of a program to address fertility preservation and parenthood after cancer treatment Joanne Frankel Kelvin 22. Psychological consultation and assessment Linda D. Applegarth 23. Nutraceuticals in fertility preservation Mark A. Moyad 24. Application of spermatogenesis suppression therapies for fertility preservation Rian J. Dickstein, Gunapala Shetty and Marvin L. Meistrich 25. Semen cryobiology and sperm banking Helen R. Levey and Bruce R. Gilbert 26. Ethical and legal considerations of sperm and tissue cryopreservation Melissa B. Brisman and Lauren Murray 27. The use of ejaculation induction procedures in cancer patients Dana A. Ohl, Mikkel Fode, Nancy L. Brackett, Charles M. Lynne, Susanne A. Quallich and Jens Sønksen 28. Sperm extraction in the pre-therapy patient Wayland Hsiao and Peter N. Schlegel 29. Fertility preservation in the pediatric population: germ cell culture and transplantation Kate H. Kraft and Thomas F. Kolon 30. Exogenous androgens: effect on spermatogenesis Mohit Khera 31. Fertility preservation in the female with cancer Kenny A. Rodriguez-Wallberg and Kutluk Oktay Part V. Post-therapy Considerations: 32. Psychological issues surrounding the use of sperm donation Allison B. Rosen and Lisa Rosenzweig 33. Medical therapy for male infertility Loren Jones and Craig Niederberger 34. Management of the varicocele in the treated patient Michael L. Eisenberg and Larry I. Lipshultz 35. Sperm extraction in the treated patient Wayland Hsiao and Peter N. Schlegel 36. Post-mortem sperm extraction Andrew C. Kramer and Ellen R. Goldmark 37. Fertility following antineoplastic therapy in the male: intrauterine insemination and the assisted reproductive technologies Hey-Joo Kang, Jack Huang and Owen K. Davis Index.