Remington: Essentials of Pharmaceutics

Remington: Essentials of Pharmaceutics provides a concise yet detailed resource covering all aspects of pharmaceutics, from the scientific fundamentals to the dosage forms and drug delivery systems to drug product analyses. The pharmaceutics section in Remington: The Science and Practice of Pharmacy, which is the most commonly used and well respected section of the book, is presented here as a single volume, designed to be portable for laboratory and classroom use. This book focuses on the pharmaceutics aspects of pharmacy practice. The text pulls heavily from the Pharmaceutics and Pharmaceutical Dosage Forms sections. Various delivery systems and dosage forms are covered as well as parenterals, sterilization processes, and sterile compounding. One chapter addresses pharmaceutical excipients and another discusses pharmaceutical packaging. Pharmaceutical analysis, product characterization, quality control, stability, bioavailability, and dissolution are also covered. Fundamental scientific concepts including thermodynamics, ionic solutions and electrolyte equilibria, tonicity, chemical kinetics, rheology, complex formation and interfacial phenomenon are presented. The text also provides an introduction to pharmacokinetics and pharmacodynamics and the principles of absorption, distribution, metabolism and excretion. In addition, some introductory concepts on drug discovery and drug product approval as well as information resources in pharmacy and the pharmaceutical sciences are presented. This book will be useful for anyone interested in pharmaceutics and drug delivery. The focus on the essential concepts of pharmaceutics and drug delivery, however, make this text an exceptionally valuable resource for scientists new to the pharmaceutical industry as well as pharmacy and graduate students. Linda Felton - Chair, Department of Pharmaceutical Sciences, Associate Professor of Pharmaceutics, University of New Mexico Albuquerque. CONTENTS   1. Information Resources in Pharmacy and the Pharmaceutical Sciences 2. Analysis of Medicinals 3. Quality Assurance and Control 4. Stability of Pharmaceutical Products 5. Bioavailability and Bioequivalency 6. Dissolution 7. Modern-day Drug Discovery and Development 8. The New Drug Approval Process 9. Metrology and Pharmaceutical Calculations 10. Statistics 11. Molecular Structure, Properties and States of Matter 12. Thermodynamics 13. Solutions and Phase Equilibria 14. Separation Methods 15. Ionic Solutions and Electrolytic Equilibria 16. Tonicity, Osmoticity, Osmolality, Osmolarity 17. Chemical Kinetics 18. Complex Formation 19. Interfacial Phenomena 20. Colloidal Dispersions 21. Coarse Dispersions 22. Rheology 23. Powders 24. Solutions, Emulsions, Suspensions, and Extracts 25. Sterilization Processes and Sterility Assurance 26. Parenteral Preparations 27. Pharmaceutical Compounding 28. Ophthalmic Preparations 29. Medicated Topicals 30. Oral Solid Dosage Forms 31. Coating of Pharmaceutical Dosage Forms 32. Oral Modified-Release Drug Delivery Systems 33. Aerosols 34. Biotechnology and Drugs 35. Pharmaceutical Packaging 36. Pharmaceutical Excipients 37. Basic Pharmacokinetics and Pharmacodynamics 38. Drug Action and Effect 39. Drug Absorption, Distribution, Metabolism and Excretion 40. Pharmacokinetics/pharmacodynamics in Drug Development