Handbook of Gastrointestinal Cancers

 Handbook of Gastrointestinal Cancers is a practical guide to the management of colorectal, pancreatic, hepatocellular, gastric, and esophageal cancers as well as other cancers of the upper and lower GI tract. Edited by a multidisciplinary group of oncologists from leading institutions, this book is an essential day-to-day reference for evidence-based treatment and patient care. The handbook focuses on treatment strategies and approaches to cancerous GI tumors that are transforming the recent oncological landscape, including expert-given guidance on methods such as neoadjuvant and adjuvant chemotherapy, surgical transplant, radiation therapy, molecular diagnostic testing leading to molecularly targeted therapy, and immunotherapy.

With so many advances in the current field, it is increasingly difficult for early-career practitioners to grasp the entirety of practices and for seasoned oncologists to keep up with newly approved therapies, side effects to treatments, and special clinical management considerations, but this handbook addresses it all. Organized by major GI disease sites and featuring "How I Treat" case vignettes from world experts for common and uncommon management considerations, the handbook brings an experience-based perspective to these tough-to-treat areas. The treatment strategies and applications set forth in the chapters are pertinent to clinical situations and clinical decision-making encountered in practice. Handbook of Gastrointestinal Cancers is a valuable resource for medical oncologists, radiation oncologists, and surgeons treating and managing gastrointestinal cancers as well as trainees in medical, radiation, and surgical oncology programs needing an accessible point of care resource.

Key Features:

    Provides treatment plans and recommendations for each stage of a range of gastrointestinal cancers, including colorectal, pancreatic, and hepatocellular cancers plus more
    Includes patient vignettes told from the physician's point of view within each clinical chapter
    Outlines special considerations for the elderly and for survivors of GI cancers
    Highlights important clinical guidance on nutritional and palliative concerns commonly seen in patients with GI cancers

Contents:

I- Colorectal Cancer:
1. Epidemiology of Colorectal Cancer: Amit Surya Narayan, Christina Wu, and Walid L. Shaib
2. Diagnosis and Staging of Colorectal Cancer: Amit Surya Narayan, Christina Wu, and Walid L. Shaib
3. Molecular Diagnostic Guidelines for Colorectal Cancer: Christine Wu, Walid L. Shaib, and Ibrahim Halil Sahin
4. How I Treat Early Stage Colon Cancer Through Surgery: Mark W. Arnold
5. How I Treat Early Stage Colon Cancer with Adjuvant Therapy: Who and How Long?: Francesca Battaglin and Heinz-Josef Lenz
6. How I Treat Early Stage Rectal Cancer with Neoadjuvant Therapy with Radiation: Nikhil Sebastian and Terence Williams
7. How I Treat Early Stage Rectal Cancer Through Surgery: Nitin Mishra
8. How I Treat Early Stage Rectal Cancer with Adjuvant Therapy: Gabriel A. Brooks
9. How I Treat Oligometastatic Colorectal Cancer Through Surgery: Rory L. Smoot and David M. Nagorney
10. How I Treat Oligometastatic Colorectal Cancer with Neoadjuvant Chemotherapy: Marwan Fakih
11. How I Treat Oligometastatic Colorectal Cancer Through Local Non-Surgical Approaches: Sadeer Alzubaidi, Alex Wallace, and Rahmi Oklu
12. How I Treat Oligometastatic Colorectal Cancer with Adjuvant Chemotherapy: Andrea Cercek and Gustavo dos Santos Fernandes
13. How I Treat Oligometastatic Colorectal Cancer with Debulking/HIPEC in Limited Peritoneal Disease: Ed Levine
14. How I Treat Metastatic Colorectal Cancer with Chemotherapy and Choice of Biologics: Kristen K. Ciombor and Satya Das
15. How I Treat Metastatic Colorectal Cancer with Maintenance Therapies: Sakti Chakrabarti and Joleen M. Hubbard
16. How I Treat Metastatic Colorectal Cancer with Emerging Therapeutic Strategies: Niharika B. Mettu and John H. Strickler
17. How I Treat Metastatic Colorectal Cancer with Immunotherapy: Michael Lam and Shubham Pant
II- Pancreatic Cancer:
18. Epidemiology of Pancreatic Cancer: Mehmet Akce, Alexandra G. Lopez-Aguiar, David A. Kooby, Field F. Willingham, Gregory B. Lesinski, and Shishir K. Maithel
19. Biological Basis for Pancreatic Cancer: Brandon Ware, Mehmet Akce, Alexandra G. Lopez-Aguiar, David A. Kooby, Field F. Willingham, Shishir K. Maithel, Gregory B. Lesinski
20. Diagnosis and Staging of Pancreatic Cancer: Ramzi Mulki, Parit Mekaroonkamol, Alexandra G. Lopez-Aguiar, Gregory B. Lesinski, David A. Kooby, Mekmet Akce, Shishir K. Maithel, and Field F. Willingham
21. The Role and Timing of Surgery in Pancreatic Cancer: Mark Truty
22. How I Treat Resectable PancreaticCancer with Adjuvant Therapy: Philip A. Philip and Mandana Kamgar
23. How I Treat Resectable Pancreatic Cancer with Neoadjuvant Therapy: Davendra P. S. Sohal
24. How I Treat Borderline Resectable and Locally Advanced Pancreatic Cancer: Hao Xie, Tanios Bekaii-Saab, and Wen Wee Ma
25. How I Treat Metastatic Pancreatic Cancer with Chemotherapy: Benjamin A. Krantz and Eileen M. O'Reilly
26. How I Treat Metastatic Pancreatic Cancer with Emerging Targets: Benjamin A. Krantz and Eileen M. O'Reilly
III- Hepatocellular Cancer:
27. Epidemiology of Hepatocellular Cancer: Safi Shahda and Bert O'Neil
28. Diagnosis and Staging of Hepatocellular Cancer: Safi Shahda and Bert O'Neil
29. Cellular and Molecular Pathology of Hepatocellular Cancer: Safi Shahda and Bert O'Neil
30. How I Treat Early-Stage Hepatocellular Cancer Through Transplant: Emmanouil Girogakis and Amit K. Mathur
31. How I Treat Early-Stage Hepatocellular Cancer Through Surgery: Rachel M. Lee and Kenneth Cardona
32. How I Treat Early-Stage Hepatocellular Cancer with Local Non-Surgical Approaches: Junaid Raja and Hyun S. Kim
33. How I Treat Early-Stage Hepatocellular Cancer with Local Non-Surgical Approaches: Jonathan B. Ashman
34. How I Treat Advanced Hepatocellular Cancer with Multikinase Inhibitors and Other Targeted Therapies: Kabir Mody and Ghassan K. Abou-Alfa
35. How I Treat Advanced Hepatocellular Cancer with Immunotherapy: Olatunji B. Alese and Katerina Zakka
IV- Gastric and Esophageal Cancer:
36. Epidemiology of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn
37. Diagnosis and Staging of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn
38. Molecular Diagnostic Guidelines of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn
39. How I Treat Early Stage Gastric and Esophageal Cancer with Neoadjuvant Therapy: William A. Stokes and Karyn A. Goodman
40. How I Treat Early Stage Gastric and Esophageal Cancer with Surgery: Sajid A. Khan, Vadim Kurbatov, and Mitchell C. Posner
41. How I Treat Metastatic Gastric and Esophageal Cancer with Chemotherapy and Choice of Biologics: Mehmet Akce
42. How I Treat Metastatic Gastric and Esophageal Cancer with Immunotherapy: Curtis R. Chong and Yelena Y. Janjigian
V- Rare Gastrointestinal Cancers:
43. Molecular Diagnostic Guidelines of Cancers of the Bile Ducts and Gallbladder: Talal Hilal and Mitesh J. Borad
44. Surgery for Early-Stage Cancers of the Bile Ducts and Gallbladder: Jordan Cloyd, Charlie Kimbrough, and Timothy M. Pawlik
45. Adjuvant Therapy for Early-Stage Cancers of the Bile Ducts and Gallbladder: Flavio G. Rocha
46. Chemotherapy for Advanced Cancers of the Bile Ducts and Gallbladder: Jonathan Whisenant
47. Emerging Therapies for Advanced Cancers of the Bile Ducts and Gallbladder: Madappa Kundranda and Milind Javle
48. Neuroendocrine Tumors: Jonathan Strosberg
49. Early-Stage Anal Cancer: Clayton A. Smith, Nitesh Rana, and Lisa A. Kachnic
50. Metastatic Anal Cancer: Saivaishnavi Kamatham, Faisal Shahjehan, and Pashtoon M. Kasi
51. Gastrointestinal Stromal Tumors (GIST): Kantha Ratnam Kolla and Mahesh Seetharam
VI- Special Clinical Considerations for Gastrointestinal Cancer Patients:
52. Nutritional Needs for Gastrointestinal Cancer Patients: Tiffany Barrett
53. Palliative Carefor Gastrointestinal Cancer Patients: Angelia Curseen
54. Care for Elderly Gastrointestinal Cancer Patients: Grant R. Williams and Hanna K. Sanoff
55. Survivorship Care for Gastrointestinal Cancer Patients: Nataliya V. Uboha, Mary Mulkerin, Stephanie L. Fricke, and Noelle K. LoConte

Tanios Bekaii-Saab, MD, FACP, is Professor of Medicine, Senior Associate Consultant of Hematology and Oncology, and Co-Leader of the Gastrointestinal Cancer Program at the Mayo Clinic Cancer Center in Scottsdale, Arizona. Prior to his move to Mayo Clinic, he earned his medical degree from the American University of Beirut in Lebanon, followed by a residency in internal medicine at Indiana University Medical Center in Indianapolis, Indiana. He completed fellowships in clinical pharmacology and experimental therapeutics and hematology/oncology at Tufts University/New England Medical Center in Boston, Massachusetts. He was previously at Ohio State University - Arthur G. James Cancer Hospital and Solove Research Institute as a tenured Professor of Medicine and Pharmacy, and Section Chief for the Gastrointestinal Cancer Program.