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This book represents the essentials of diagnostic cytopathology. Clinical research has confirmed the efficacy of the cytologic method of disease diagnosis and it is now considered the definitive method for identifying a wide array of malignancies. Cytohistology: Essential and Basic Concepts comprehensively covers all the morphologic variations and landmarks in cells that can potentially signal disease. Morphologies in cancer are the primary focus but all potential changes in infectious and inflammatory disorders are also covered in detail. There is a separate section on molecular and other ancillary diagnostic techniques in cytopathology. Conceptual drawings presented in a pansystemic approach and incorporating state-of-the-art techniques show basic cytomorphologic features essential for interpretation of cytopathology specimens. Diagnostic pitfalls and challenging intellectual nuggets are also presented. A supplementary CD with images in a downloadable format is included. Edited by: Prabodh Gupta, University of Pennsylvania School of Medicine Edited by: Zubair Baloch, University of Pennsylvania School of Medicine Features • Includes a CD with images in a downloadable format • A pansystemic approach: diagnostic value in specimens procured from all major body sites • Incorporates ancillary studies and the use of state-of-the-art techniques Table of Contents 1. Historical perspective Prabodh K. Gupta and Zubair W. Baloch 2. Fixation and specimen processing Gary Gill 3. Normal cell morphology euplasia (cells in health and physiologic state) Prabodh K. Gupta and Zubair W. Baloch 4. Malignant cell morphology Prabodh K. Gupta and Zubair W. Baloch 5. Functional differentiation characteristics in cancer Prabodh K. Gupta and Zubair W. Baloch 6. Altered pan epithelial functional activity Prabodh K. Gupta and Zubair W. Baloch 7. Ancillary techniques applicable to diagnostic cytopathology Carlos Bedrossian Index.