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There have been numerous major advances in clinical trial methodology and this superb book will cover all developments in this important field. Written as a successor to the outstandingly successful book by Pocock 'Clinical Trials', it will provide up to date coverage of the topics covered in the original text whilst retaining the same authoritative and didactic approach. It will appeal to a wide readership including clinicians and data managers as well as medics and health care professionals who need to know the simple statistical issues in trials and statisticians who need to know about the medical and other non-statistical aspects of trials. CONTENTS 1. Introduction 2. Design Features 3. The Trial Protocol 4. Measurement and Data Capture 5. Randomisation 6. Trial Initiation 7. Trial Conduct 8. Basics for Analysis 9. Trial Size 10. Reporting 11. Adaptations of the Basic Design 12. Paired Designs 13. More than Two Interventions
John Wiley and Sons Ltd
December 7, 2007
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