• Shop
  • Publish
  • Prints & Productions
  • Learning solutions for businesses
Forgot your password?

I don't have an Acco-account yet and want to register now

Create an account
0
accouitgeverij.nl
en
Nederlands English
View all Show all results
results in specialist areas
View all results
Course materials
KU Leuven (Leuven en Heverlee) KULAK KUL Brugge Nabestellingen KU Leuven IIW De Nayer Universiteit Antwerpen Universiteit Gent

Specialist literature
  • Medical
  • Literature and fiction
  • Philosophy and religion
  • History
  • Economics
  • Law, criminology and notaryship
  • Linguistics
  • Science and technology
  • Travel, recreation and cooking
  • Art and culture
  • Psychology
  • Education and teaching
  • Politics and social sciences
  • Veterinary
  • Office supplies
  • For Students Only

Office supplies
Online printservice
Buy your Acco share
About Acco Shops Buy your Acco share Jobs Customer service Contact

en
Nederlands English
Course materials
KU Leuven (Leuven en Heverlee) KULAK KUL Brugge Nabestellingen KU Leuven IIW De Nayer Universiteit Antwerpen Universiteit Gent
Specialist literature
  • Medical
  • Literature and fiction
  • Philosophy and religion
  • History
  • Economics
  • Law, criminology and notaryship
  • Linguistics
  • Science and technology
  • Travel, recreation and cooking
  • Art and culture
  • Psychology
  • Education and teaching
  • Politics and social sciences
  • Veterinary
  • For Students Only
Office supplies Online printservice
Buy your Acco share
View all Show all results
results in specialist areas
View all results
Home Metabolic Syndrome

Metabolic Syndrome

Underlying Mechanisms and Drug Therapies

Minghan Wang
Endocrinology - general
Book
  • Metabolic Syndrome - 9780470343425
€120.80
€120.79 with an Acco share
Estimated time of delivery: plus 4 working days
  • with an Acco share you get a discount on Acco-titles, office supplies and selected titles.
Content
This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug development. The authors examine the context of underlying molecular pathways and integrated physiology, then expanding the discussion to diseases associated with metabolic syndrome. The development of drug therapies for these diseases and complications is extensively covered. The book offers a comprehensive and in-depth view of energy metabolism, metabolic tissues and pathways, molecular mechanism-based drug discovery and clinical implications. CONTENTS Introduction (Minghan Wang). Part I. The physiology of metabolic tissues under normal and disease states. Chapter 1: Gut as an endocrine organ: the role of nutrient-sensing in energy metabolism (Minghan Wang). Chapter 2: Central glucose sensing and control of food intake and energy homeostasis (Lourdes Mounien and Bernard Thorens). Chapter 3: Abnormalities in insulin secretion in type 2 diabetes mellitus (Taly Meas and Pierre-Jean Guillausseau). Chapter 4: Adipokine production by adipose tissue: A novel target for treating metabolic syndrome and its sequelae (Vanessa DeClercq, Danielle Stringer, Ryan Hunt, Carla G. Taylor, and Peter Zahradka). Chapter 5: Hepatic metabolic dysfunctions in type 2 diabetes: Insulin resistance and impaired glucose production and lipid synthesis (Ruojing Yang). Chapter 6: Energy metabolism in skeletal muscle and its link to insulin resistance (Minghan Wang). Part II. Metabolic diseases and current therapies. Chapter 7: Mechanisms and complications of metabolic syndrome (Minghan Wang). Chapter 8: Emerging therapeutic approaches for dyslipidemia associated with high LDL and low HDL (Margrit Schwarz and Jae B. Kim). Chapter 9: Mechanism of action of niacin: implications for atherosclerosis and drug discovery (Devan Marar, Shobha H. Ganji, Vaijinath S. Kamanna, and Moti L. Kashyap). Chapter 10: Current anti-diabetic therapies and mechanisms (Minghan Wang). Part III. Drug targets for anti-diabetic therapies. Chapter 11: GLP-1 biology, signaling mechanisms, physiology, and clinical studies (Remy Burcelin, Cendrine Cabou1, Christophe Magnan, and Pierre Gourdy). Chapter 12: Dipeptidyl peptidase IV inhibitors for treatment of diabetes (McIntosh, CHS, Kim, S-J., Pederson, RA, Heiser, U, and Demuth, H-U). Chapter 13: Sodium glucose co-transporter 2 inhibitors (Margaret Ryan and Serge A. Jabbour). Chapter 14: Fibroblast growth factor 21 as a novel metabolic regulator (Radmila Micanovic, James D. Dunbar, and Alexei Kharitonenkov). Chapter 15: Sirtuins as potential drug targets for metabolic diseases (Qiang Tong). Chapter 16: 11?-hydroxysteroid dehydrogenase type 1 as a therapeutic target for type 2 diabetes (Clarence Hale and David J. St. Jean, Jr.). Chapter 17: Monoclonal antibodies for the treatment of type 2 diabetes: A case study with glucagon receptor blockade (Hai Yan, Wei Gu, and Murielle Veniant-Ellison). Part IV. Lessons learned and future outlook. Chapter 18: Drug development for metabolic diseases: past, present and future (Minghan Wang).
Specifications
Publisher
John Wiley and Sons Ltd
Publication date
January 14, 2011
Pages
496
ISBN
9780470343425
Format
Hardback

More titles in this specialist area

The Pituitary
The Pituitary
Shlomo Melmed
€166.02
€166.01 with an Acco share
This product is not available
The Pituitary
Practical Pediatric Endocrinology in a Limited Resource Setting
Practical Pediatric Endocrinology in a Limited Resource Setting
Margaret Zacharin
€73.04
€73.03 with an Acco share
This product is not available
Practical Pediatric Endocrinology in a Limited Resource Setting
Cellular Endocrinology in Health and Disease
Cellular Endocrinology in Health and Disease
Alfredo Ulloa-Aguirre P. Michael Conn
€126.18
€126.17 with an Acco share
This product is not available
Cellular Endocrinology in Health and Disease
Osteoporosis
Osteoporosis
David W. Dempster David Feldman Jane A. Cauley Marjorie Luckey Robert Marcus
€365.00
This product is not available
Osteoporosis
Osteoimmunology
Osteoimmunology
Mark Horowitz Yongwon Choi Hiroshi Takayanagi Georg Schett Joseph Lorenzo
€114.50
This product is not available
Osteoimmunology
Genomic and Precision Medicine: Inflammatory and Metabolic Disease
Genomic and Precision Medicine: Inflammatory and Metabolic Disease
- Willard - Ginsburg
€105.99
This product is not available
Genomic and Precision Medicine: Inflammatory and Metabolic Disease

Do you have a question?

Our customer service is happy to help. Consult our frequently asked questions or contact us.

This item is being added to your cart
This item has been added to your cart
To cart
Keep me informed
Your email address has been noted.
We will inform you when this item is available again.
Shop
  • Course materials
  • Specialist literature
  • Office supplies
  • Online printservice
Publisher
  • Publishing
  • Blended learning
  • Good practices & Blogs
Print & Productions
  • Doctoral thesis
  • Online printservice
  • Printservice in our shops
Learning solutions for businesses
  • How we work
  • The 4-layer model
  • Our team
Acco
  • Shops
  • Acco-share
  • Customer service
  • Contact

Newsletter

Stay informed with the latest news from Acco

Stay up-to-date with our latest news. You can read more about how we process your data in our privacy policy.
Acco • Terms and conditions • Privacy policy • Cookie settings
BE 0403 547 615
facebook linkedin instagram
BE 0403 547 615

De Smidse, Sluisstraat 10, 3000 Leuven

Map
You need a code for this download
Your code is incorrect.
Log in
Forgot your password?
Not registered yet?

Create an account to buy or link an Acco share and buy your books and supplies at reduced rates.

Sign up