From the classroom to the lab, this text provides complete coverage of the latest advances in clinical chemistry. Part one of the text includes content on laboratory techniques and practice, and part two provides detailed descriptions of how specific diseases affect the human body. Plenty of user-friendly features including outlines, key terms, objectives, and internet references make even difficult concepts easy to understand, and the new full-color insert illustrates important concepts in vibrant detail. Table of Contents Part I: Laboratory Techniques and Laboratory Management 1. Basic Laboratory Principles and Techniques 2. Spectral Techniques 3. Chromatography and Mass Spectrometry: Theory, Practice, and Instrumentation 4. Chromatographic Techniques 5. Laboratory Analysis of Hemoglobin Variants NEW! 6. Electrophoresis 7. Immunological Reactions 8. Immunochemical Techniques 9. Principles for Competitive-Binding Assays 10. Laboratory Approaches to Serology Testing NEW! 11. Measurement of Colligative Properties 12. Electrochemistry: Principles and Measurement 13. Molecular Diagnostics 14. Therapeutic Drug Monitoring 15. Clinical Enzymology 16. Protein Isoforms: Isoenzymes and Isoforms 17. Interferences in Chemical Analysis 18. Sources and Control of Preanalytical Variation 19. Laboratory Management 20. Laboratory Automation 21. Point-of-Care (Near-Patient) Testing 22. Laboratory Information Systems 23. Laboratory Statistics 24. Reference Intervals and Clinical Decision Limits 25. Quality Control in the Clinical Chemistry Laboratory 26. Evaluation of Methods Part II: Physiology and Pathophysiology 27. Basic Biochemistry 28. Physiology of Body Water and Electrolytes 29. Acid-Base Control and Acid-Base Disorders 30. Renal Function 31. Liver Function 32. Viral Hepatitis: Diagnosis and Monitoring NEW! 33. Bone Disease 34. The Pancreas: Function and Chemical Pathology 35. Gastrointestinal Function 36. Cardiac and Muscle Disease 37. Coronary Artery Disease: Lipid Metabolism 38. Diabetes 39. Iron, Porphyrin, and Bilirubin Metabolism 40. Hemoglobin 41. Human Nutrition 42. Trace Metals 43. Vitamins 44. Pregnancy 45. The Newborn 46. Extravascular Biological Fluids 47. Nervous System 48. General Endocrinology 49. Thyroid 50. The Gonads 51. Adrenal Hormones and Hypertension 52. Diseases of Genetic Origin 53. Neoplasia 54. Laboratory Evaluation of the Transplant Recipient 55. Toxicology 56. Addiction and Substance Abuse