Asthma

Asthma sufferers number approximately 200 million worldwide, with 15-20 million of those in the United States. Multiple comorbid conditions occur with asthma, including rhinitis, rhinosinusitis, gastroesophageal reflux disease, sleep apnea, vocal cord dysfunction syndrome, obesity, and chronic obstructive pulmonary disease (COPD). Without identifying and caring for comorbid conditions, asthma cannot be treated appropriately. Comorbidity of allergic diseases emphasizes that we must understand more about why different organs in individuals express allergy and others do not. The increase in multiple allergies occurring in a single patient makes the global burden even more complex, and an integrated approach to diagnosis and new treatment strategies and preventative approaches are required. Asthma: Comorbidities, Coexisting Conditions, and Differential Diagnosis is the first volume to provide a centralized, a comprehensive clinical reference on the diagnosis and management of the comorbid conditions that affect asthma. Because comorbid conditions of asthma have not yet been included in international and national management guidelines, this volume will help fill a gap in current clinical knowledge, aiding physicians in delivering optimal patient care. Written and published in conjunction with the World Allergy Organization (WAO), this book consists of the latest research and reviews of current theory and practice, the most effective advances in the diagnosis and management of asthma and its co-morbidities, and insights into the fundamentals of asthma and its co-morbidities. It presents scientifically-based medicine for each comorbid condition as it relates to asthma. Richard F. Lockey, MD, Professor of Medicine, Pediatrics and Public Health, Director, Division of Allergy and Immunology, Joy McCann Culverhouse Chair in Allergy and Immunology, University Distinguished Health Professor, Asthma, Allergy & Immunology Clinical Research Unit, University of South Florida College of Medicine, James A. Halley Veterans Hospital, USA, Edited by Dennis K. Ledford, MD, Professor of Medicine and Pediatrics, Asthma Allergy & Immunology Clinical Research Unit, Division of Allergy and Immunology, University of South Florida College of Medicine, James A. Haley Veterans Administration Hospital, USA, and With WAO , World Allergy Organization, USA CONTENTS Section 1 - Immunologic 1. Hypersensitivity Pneumonitis 2. Anti-neutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis 3. Allergic Bronchopulmonary Aspergillosis (ABPA) 4.Immunodeficiency: Innate, Primary and Secondary Section 2 - Pulmonary 5. Sleep Apnea - Comorbid and Coexisting - in Children and the Upper Airway 6. Asthma and Obstructive Sleep Apnea 7. COPD and Irreversible Airflow Obstruction 8. Bronchiectasis 9. Bronchiolitis 10. Genetic Disorders and Asthma 11. Other Pulmonary Abnormalities 12. Pneumonia - Comorbid and Co-existing 13. Cough 14. Occupational Asthma - Comorbid and Differential Diagnosis Section 3 - Cardiac & Cardiovascular 15. Adult Cardiac Conditions 16. Pediatric Cardiac Conditions - Coexisting and Differential Diagnosis 17. Pulmonary Hypertension Section 4 - Upper/Extrathoracic Airway 18. Allergic Rhinitis 19. Nonallergic Rhinopathies and Lower Airway Syndromes 20. Infectious Comorbidities of Asthma in the Upper Airway 21. Nasal Polyps - Comorbid 22. Vocal Cord Dysfunction and Paradoxical Vocal Fold Motion Disorder Section 5 - Gastrointestinal 23. Gastroesophageal Reflux Section 6 - Metabolic 24. Obesity and Asthma 25. Endocrine Disorders - Comorbid and Coexisting 26. Osteopenia and Osteoporosis: Comorbidities of Asthma 27. Pregnancy - Comorbid and Coexisting Section 7 - Psychological Issues 28. Psychological Factors - Comorbid and Coexisting 29. Asthma, Substance Abuse, and Tobacco Use Section 8 - Exercise 30. Exercise-induced Bronchoconstriction and Asthma Section 9 - Environmental & Population Effects 31. Environmental Risk Factors in Asthma Section 10 - Age 32. Age and Asthma Section 11 - Food 33. Atopic Dermatitis, Food Allergy and Anaphylaxis - Comorbid and Coexisting

Richard F. Lockey, MD, Professor of Medicine, Pediatrics and Public Health, Director, Division of Allergy and Immunology, Joy McCann Culverhouse Chair in Allergy and Immunology, University Distinguished Health Professor, Asthma, Allergy & Immunology Clinical Research Unit, University of South Florida College of Medicine, James A. Halley Veterans Hospital, USA, Edited by Dennis K. Ledford, MD, Professor of Medicine and Pediatrics, Asthma Allergy & Immunology Clinical Research Unit, Division of Allergy and Immunology, University of South Florida College of Medicine, James A. Haley Veterans Administration Hospital, USA, and With WAO , World Allergy Organization, USA