Oxford Textbook of Clinical Neurophysiology

Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Clinical Neurophysiology includes sections that provide a summary of the basic science underlying neurophysiological techniques, a description of the techniques themselves, including normal values, and a description of the use of the techniques in clinical situations. Much of diagnostic neurophysiology is essentially pattern recognition which is illustrated throughout the text using audio and video examples.

Divided into four key sections, this book begins with the scientific basis of clinical neurophysiology (Section 1) before exploring specific techniques including Electromyography, Intracranial EEG recordings, and Magnetoencephalography (Section 2). The final two sections explore clinical aspects of both the peripheral nervous system (Section 3) and the central nervous system (Section 4).

Contents

Section 1: Scientific basis of clinical neurophysiology
1: Nerve, muscle and neuromuscular junction, Machiel J. Zwarts
2: The motor unit, David Burke and James Howells
3: Motor control: Spinal and cortical mechanisms, David Burke
4: Cortical activity: Single cell, cell assemblages and networks, John G. R. Jefferys
5: Recording of neural signals, neural activation and signal processing, Dick F. Stegemann and Michel J. A. M. van Putten
Section 2: Techniques of clinical neurophysiology
6: Nerve conduction studies, Jun Kimura
7: Electromyography, Erik Stålberg
8: Quantitative EMG, Anders Fuglsang-Frederiksen, Kirsten Pugdahl, and Hatice Tankisi
9: Axonal excitability: Molecular basis and assessment in the clinic, Susanna B. Park, Cindy S-Y Lin, and Matthew C. Kiernan
10: Reflex studies, Josep Valls-Solé
11: Electroencephalography, Michalis Koutroumanidis, Dimitrios Sakellariou, and Vasiliki Tsirka
12: Intracranial EEG recordings, Gonzalo Alarcón and Antonio Valentín
13: Magnetoencephalography, Paul L. Furlong, Elaine Foley, Caroline Witton, and Stefano Seri
14: Transcranial magnetic stimulation, Kerry R. Mills
15: Evoked potentials, Helmut Buchner
16: Polysomnography and other investigations for sleep disorders, Zenobia Zaiwalla and Roo Killick
17: Clinical neurophysiology of the pelvic floor, Adrian J. Fowle
Section 3: Clinical aspects: peripheral nervous system
18: The clinical approach to neurophysiology, Kerry R. Mills
19: Focal neuropathies, Jeremy D. P. Bland
20: Generalised peripheral neuropathies, Hessel Franssen
21: Disorders of single nerves, roots and plexuses, Kerry R. Mills
22: Neurophysiology in ALS and other motor degenerations, Mamede de Carvalho and Michael Swash
23: Clinical aspects of neuromuscular junction disorders, Donald B. Sanders
24: Primary muscle diseases, Robin P. Kennett and Sidra Aurangzeb
25: Paediatric conditions, Matthew Pitt
26: EMG guided botulinum toxin therapy, V. Peter Misra and Santiago Catania
Section 4: Clinical aspects: central nervous system
27: Genetic generalized epilepsy, Friederike Moeller, Ronit M. Pressler, and J. Helen Cross
28: Focal epilepsy, Tim Wehner, Kanjana Unnwongse, and Beate Diehl
29: Syncope, Shane Delamont
30: Convulsive and non-convulsive status epilepticus, Matthew C. Walker
31: Presurgical evaluation for epilepsy surgery, Robert Elwes
32: Encephalopathy, CNS infections and coma, Michalis Koutroumanidis and Robin Howard
33: Migraine, stroke and cerebral ischaemia, Gonzalo Alarcón, Marian Lazaro, and Antonio Valentín
34: Electroclinical features of paediatric conditions, Sushma Goyal
35: Sleep disorders, Zenobia Zaiwalla and Roo Killick
36: Intraoperative monitoring, Marc R. Nuwer

Kerry R. Mills, Professor of Clinical Neurophysiology, Department of Clinical Neurosciences, King's College London, UK

Kerry R. Mills is Professor of Clinical Neurophysiology and Honorary Consultant Clinical Neurophysiologist, King's College Hospital, as well as Honorary Consultant Clinical Neurophysiologist at Guy's Hospital, London. He is also Honorary Professor at the University of Thessaloniki and he was formerly Professor of Clinical Neurophysiology and Consultant Clinical Neurophysiologist at the University of Oxford and The Radcliffe Infirmary 1987 to 1999. He has maintained continuous research output from 1975 to the present day, with over 230 peer reviewed publications, chapters and one single author book. Additionally, he is currently an Emeritus Fellow at Green College, Oxford.

Contributors:

Gonzalo Alarcón, Comprehensive Epilepsy Center Neuroscience Institute, Hamad Medical Corporation, Doha, Qatar; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; Departamento de Fisiología, Facultad de Medicina, Universidad Complutense, Madrid, Spain

Sidra Aurangzeb, Oxford University Hospitals NHS Trust, UK

Jeremy D. P. Bland, East Kent Hospitals University NHS Foundation Trust, UK

Helmut Buchner, Department of Neurology and Clinical Neurophysiology, Klinikum Vest Hospital, Recklinghausen, Germany

David Burke, Department of Neurology, Royal Prince Alfred Hospital and University of Sydney, Australia

Mamede de Carvalho, Institute of Physiology, Faculty of Medicine, Instituto de Medicina Molecular, University of Lisbon, Portugal; Department of Neurosciences, Hospital de Santa Maria-CHLN, Lisbon, Portugal

Santiago Catania, The National Hospital for Neurology and Neurosurgery, London, UK

J. Helen Cross, Clinical Neurosciences Section, UCL Institute of Child Health, Great Ormond Street Hospital for Children, London, UK

Shane Delamont, Consultant Neurologist, Department of Neurology and Neurophysiology, King's College Hospital, London, UK

Beate Diehl, Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, UK; Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery, London, UK

Robert Elwes, King's College Hospital, London, UK

Elaine Foley, Aston Brain Centre, School of Life and Health Sciences, Aston University, Birmingham, UK

Adrian J. Fowle, West Surrey Clinical Neurophysiology, Ashford and St Peter's Hospitals NHS Foundation Trust, Chertsey, UK

Hessel Franssen, Department of Neuromuscular Disorders, Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands

Anders Fuglsang-Frederiksen, Department of Clinical Neurophysiology, Aarhus University Hospital, Denmark

Paul L. Furlong, Aston Brain Centre, School of Life and Health Sciences, Aston University, Birmingham, UK

Sushma Goyal, Evelina London Children's Hospital, Puffin EEG Department, St Thomas' Hospital, London, UK

Robin Howard, Department of Neurology, The National Hospital for Neurology, Neurosurgery and Psychiatry, London, UK

James Howells, Brain and Mind Centre, University of Sydney, Australia

John G. R. Jefferys, Department of Pharmacology, University of Oxford, UK

Robin P. Kennett, Oxford University Hospitals NHS Trust, UK

Matthew C. Kiernan, Brain and Mind Centre and Sydney Medical School, University of Sydney, Australia

Roo Killick, Woolcock Institute of Medical Research, University of Sydney, NSW, Australia

Jun Kimura, Department of Neurology, University of Iowa Health Care, Iowa City, USA

Michalis Koutroumanidis, Department of Neurology and Department of Clinical Neurophysiology and Epilepsy, Guy's and St Thomas' NHS Foundation Trust, London, UK

Marian Lazaro, Nerve and Brain Studies Department, Guy's and St Thomas NHS Foundation Trust, London, UK; Neurophysiology Department, Evelina London Children's Hospital , St Thomas' Hospital, London, UK

Cindy S-Y Lin, Translational Neuroscience Facility, School of Medical Sciences, University of New South Wales, Australia

Kerry R. Mills, Department of Basic and Clinical Neuroscience, King's College London, UK

V. Peter Misra, Imperial College Heathcare NHS Trust, Hammersmith Hospital, London, UK

Friederike Moeller, Department of Neurophysiology, Great Ormond Street Hospital for Children, London, UK

Marc R. Nuwer, Department of Neurology, David Geffen School of Medicine, Ronald Reagan UCLA Medical Center, University of California, Los Angeles, USA

Susanna B. Park, Brain and Mind Centre and Sydney Medical School, University of Sydney, Australia

Matthew Pitt, Department of Clinical Neurophysiology, Great Ormond Street Hospital for Children, London, UK

Ronit M. Pressler, Clinical Neurosciences Section, UCL Institute of Child Health, Great Ormond Street Hospital for Children, London, UK

Kirsten Pugdahl, Department of Clinical Neurophysiology, Aarhus University Hospital, Denmark

Michel J. A. M van Putten, Hospital Medisch Spectrum Twente, Department of Clinical Neurophysiology and Clinical Neurophysiology (CNPH), MIRA-Institute for Biomedical Technology and Technical Medicine, Faculty of Science and Technology, University of Twente, Enschede, the Netherlands

Dimitrios Sakellariou, Department of Clinical Neurophysiology and Epilepsy, Guy's and St Thomas' NHS Foundation Trust, London, UK; Department of Academic Neurosciences, King's College London, UK; Neurophysiology Unit, Department of Physiology, School of Medicine, University of Patras, Greece

Donald B. Sanders, Duke University Medical Center, Durham, NC, USA

Stefano Seri, Aston Brain Centre, School of Life and Health Sciences, Aston University, Birmingham, UK

Erik Stålberg, Department of Clinical Neurophysiology, Section of Neuroscience, Uppsala University, Sweden

Dick F. Stegemann, Radboud University Medical Center Nijmegen, Department of Neurology/ Clinical Neurophysiology, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, the Netherlands

Michael Swash, Barts & the London School of Medicine, Queen Mary University of London, UK; Royal London Hospital, UK; University of Lisbon, Portugal

Hatice Tankisi, Department of Clinical Neurophysiology, Aarhus University Hospital, Denmark

Vasiliki Tsirka, Department of Clinical Neurophysiology and Epilepsy, Guy's and St Thomas' NHS Foundation Trust, London, UK; Department of Academic Neurosciences, King's College London, UK

Kanjana Unnwongse, Neurology Department, Prasat Neurological Institute, Bangkok, Thailand

Antonio Valentín, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; Departamento de Fisiología, Facultad de Medicina, Universidad Complutense, Madrid, Spain

Josep Valls-Solé, EMG Unit, Neurology Department, University of Barcelona, Hospital Clinic, Barcelona, Spain

Matthew C. Walker, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London, UK

Tim Wehner, Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, UK; Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery, Queen Square , London, UK

Caroline Witton, Aston Brain Centre, School of Life and Health Sciences, Aston University, Birmingham, UK

Zenobia Zaiwalla, John Radcliffe Hospital, Oxford, UK

Machiel J. Zwarts, Kempenhaeghe, Academic Centre for Epilepsy, Heeze, The Netherlands