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Evidence-based medicine is a concept that is at the forefront of anaesthesia. Clinicians are increasingly encouraged to practise patient management based on available evidence in the scientific literature. For example, new anaesthesia methods, e.g. regional anaesthesia, are being used more frequently based on case studies that show the efficacy and cost-savings associated with the treatment. Additionally, considering that many anaesthetists are required to cover a range of areas, information discussing proven methods as well as pitfalls to avoid are valuable to all those working in the field. This book provides a detailed summary of the most important trials and studies in anaesthesia, ranging from neuroanaesthesia and anaesthesia for transplant, to paediatric and thoracic anaesthesia, allowing the reader to rapidly extract key results. Each chapter is written by a prominent anaesthetist in that particular field, and papers have been selected on a number of criteria, included impact factor, authors' choices, or even because the conclusions reached do not indicate best practice. With this wealth of information collected into this newest volume in the 'Landmark Papers in' series, Landmark Papers in Anaesthesia is essential reading for all practicing anaesthetists. Table of Contents 1. Neuromuscular blockade ; 2. Anaesthetic equipment ; 3. Inhaled and Intravenous anaesthetics ; 4. Total intravenous anaesthesia ; 5. Monitoring ; 6. Optimization ; 7. Complications of anaesthesia ; 8. Mechanisms of anaesthesia ; 9. Local anaesthesia ; 10. Perioperative cardioprotection ; 11. Neuroanaesthesia ; 12. Thoracic anaesthesia ; 13. Anaesthesia for vascular surgery ; 14. Anaesthesia for major abdominal surgery ; 15. Liver transplantation anaesthesia ; 16. Obstetric anaesthesia ; 17. Airway management ; 18. Paediatric anaesthesia ; 19. Malignant hyperthermia