Oxford Textbook of Axial Spondyloarthritis

Axial Spondyloarthritis is a timely addition to the Oxford Textbooks in Rheumatology series, providing a comprehensive reference to this rapidly evolving field. The conceptual framework of the disease has now evolved beyond ankylosing spondylitis to encompass a broader concept of axial inflammation. Earlier recognition has opened the door to earlier intervention, and the understanding of the biologic basis of axial SpA has seen significant advances in recent years.

The first textbook to cover axial spondyloarthritis in this level of detail from a global perspective, this volume offers a practical and complete resource compiled by a multidisciplinary and multinational team of experts. Beginning with a historical perspective on the disease, the textbook provides a comprehensive background in the epidemiology, diagnosis, and classification of axial spondyloarthritis. Immune mechanisms and genetics are covered, along with imaging and a detailed section on the range of treatments options currently available. A section on extra-articular manifestations provides a comprehensive knowledge base for the clinician treating patients with spondyloarthritis, and chapters on the economics of the disease, physical functioning, and patient registries complete the broad coverage of the topic.

Practical, easy to use, yet detailed with respect to pathophysiology, diagnostics, and management, this textbook provides a comprehensive reference for rheumatologists, general practitioners, internists, and paediatricians managing patients with axial spondyloarthritis.

Contents

1: Spondyloarthritis in antiquity and in history, Bruce Rothschild & Ernst Feldtkeller
2: Epidemiology of Axial Spondyloarthritis, Michael Weisman & Lianne Gensler
3: Diagnosis and classification of Axial Spondyloarthritis, Floris van Gaalen, Désirée van der Heijde, & Maxime Dougados
4: Diagnosis, classification, and management of Peripheral Spondyloarthritis, Martin Rudwaleit & Atul Deodhar
5: Genetics of Spondyloarthritis, Matthew Brown & John Reveille
6: Immune mechanisms: HLA-B27, Robert A. Colbert & Paul Bowness
7: Immune mechanisms: Innate immunity, Dominique Baeten
8: Immune mechanisms: Adaptive immunity, Maxime Breban & Hill Gaston
9: Infection and Spondyloarthritis, Marjatta Leirisalo-Repo & John Carter
10: Pathology: Bone, Georg Schett & Rik Lories
11: Clinical features, Filip van den Bosch & Muhammad A. Khan
12: Clinical outcomes, Robert Landewe & Astrid van Tubergen
13: Imaging: Sacroiliac joints, Walter Maksymowych & Robert Lambert
14: Imaging: Spine, Kay-Geert A. Hermann & Xenofon Baraliakos
15: Juvenile-onset Spondyloarthritis, Rubén Burgos-Vargas & Shirley Tse
16: Extra-articular manifestations: Uveitis, James Rosenbaum
17: Extra-articula manifestations: Inflammatory Bowel Disease, Dirk Elewaut, Heleen Cypers, Matthew L. Stoll, & Charles O. Elsen
18: Extra-articular manifestations: Psoriasis, Dafna Gladman & Wolf-Henning Boehncke
19: Treatment: Non-pharmacological, Salih Ozgocmen & Laura Passalent
20: Treatment: Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis, Nigil Haroon & Jon Chan
21: Treatment: DMARDS, Denis Poddubnyy & Hildrun Haibel
22: Treatment: Biologics, Juergen Braun & Irene van der Horst-Bruinsma
23: Treatment: Aim and indication of surgical treatment, Heinrich Boehm & Y. Raja Rampersaud
24: Patient registries, Tore Kristian Kvien, Mikkel Østergaard, & Elisabeth Lie
25: Economic evaluation of diagnosing and treating axial SpA, Annelies Boonen
26: Physical functioning and work ability, Michael Ward
27: Patient support and advocacy in Axial Spondyloarthritis, Laure Savage & Seoirse Smith
28: Axial Spondyloarthritis in Asia, Tae Hwan Kim, Huji Xu, Chan-Bum Choi, & Feng Huang
29: Axial Spondyloarthritis in Latin America, Percival Sampaio-Barros & Rafael Valle Onate
30: Axial Spondyloarthritis in India, Anand Malaviya & Ashok Kumar

Robert Inman, Director Spondylitis Program, University Health Network, Department of Medicine, University of Toronto, Canada, and Joachim Sieper, Department of Rheumatology, Charite University Hospital, Berlin, Germany

Robert D. Inman completed his undergraduate degree at Yale University, and his medical degree at McMaster University. He did his training in Internal Medicine at Vanderbilt University and his fellowship in Rheumatology at Cornell University, based at the Hospital for Special Surgery. He worked as a research fellow at the Hammersmith Hospital in London, then was appointed Assistant Professor of Medicine at Cornell University. He moved to the University of Toronto where he was appointed Professor in the Departments of Medicine and Immunology. He was Director of Rheumatology at the University of Toronto 1991-2002. Dr Inman is currently Director of the Arthritis Center of Excellence at the University Health Network, Director of the Spondylitis Program at Toronto Western Hospital, and Deputy Physician in Chief, Research at University Health Network.

Joachim Sieper is Head of the Department of Rheumatology at the Charite University Hospital, Berlin, Germany. Prof. Sieper was a Full member of the Medicines Commission 2002-2010, and has been an Extraordinary member of the Drug Commission since 2011.