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This fifth edition of the Autonomic Failure covers the many recent advances made in our understanding of the autonomic nervous system. There are numerous new chapters and extensive revisions of all other contributions. This volume makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. It continues to provide a rational guide to aid in the recognition and management of autonomic disorders for practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine. Edited by Christopher J. Mathias, Neurovascular Medicine Unit, Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, St Mary's Hospital, London, UK, and Sir Roger Bannister, Former Master, Pembroke College Oxford; Honorary Consultant Physician, National Hospital for Neurology and Neurosurgery, London; Honorary Consultant Neurologist, St. Mary's Hospital, London, Oxford District Health Authority and Oxford Regional Health Authority, UK CONTENTS Roger Bannister and Christopher Mathias: Introduction - Tilli Tansy: Historical perspectives on the autonomic nervous system - 1: Wilfrid Janig and Elspeth M McLachlan: Neurobiology of the autonomic nervous system - 2: Stephen J Peroutka: Molecular genetics and the autonomic nervous system - 3: Eduardo E Benarroch: Neurotransmitters and neuromodulators in the CNS and cardiovascular regulation - 4: Mike Schachter: Adrenergenic and cholingeric receptors - 5: Geoffrey Burnstock: Structural and chemical organization of the autonomic nervous system with special reference to non-adrenergic, non-cholinergic transmission - 6: Michael A. Moskowitz, Melanie C. Sharp and Robert McFarlane: Autonomic and neurohormonal control of the cerebral circulation - 7: Hugo D. Critchley and Christopher J. Mathias: Functional neuroimaging of autonomic control - 8: Bill J.Yates and Adolfo Bronstein: Vestibular system influences on respiratory muscle activity and cardiovascular functions - 9: Peter J Goadsby: Autoregulation and autonomic control of the cerebral circulation: implications and pathophysiology - 10: Kenneth J Collins: Temperature regulation and the autonomic nervous system - 11: Ralf Baron and Wilfrid Janig: Mechanisms underlying complex regional pain syndrome: Role of the sympathetic nervous system - 12: Peter J Barnes: Autonomic control of the airways - 13: Anne E Bishop and Julia M Polak: The gut and the autonomic nervous system - 14: Paul L R Andrews: Nausea, vomiting, and the autonomic nervous system - 15: Ian A Macdonald: The influence of the autonomic nervous system on metabolic function - 16: Edward J Johns: The kidney and the sympathetic nervous system - 17: William C de Groat: Neural control of the urinary bladder - 18: Stacy Elliot: Investigation and treatment of sexual dysfunction in autonomic diseases - 19: Christopher J Mathias, David Low, Valeria Iodice and Roger Bannister: Investigation of autonomic disorders - 20: Wouter Wieling and John M Karemaker: Measurement of heart rate and blood pressure to evaluate disturbances in neurocardiovascular control - 21: G Parati, M Di Rienzo, P Castiglioni and G Mancia: Computer analysis of blood pressue and heart rate variability in subjects with normal and abnormal autonomic cardiovascular control - 22: J F R Paton and K M Spyer: Central nervous control of cardiovascular system - 23: Antonio Claudio Lucas da Nobrega, David A Low and Christopher J Mathias: Exercise-induced hypotension in autonomic disorders - 24: Christopher J Mathias, Karen Jones and Roger Bannister and Karen Jones: Postprandial hypotension in autonomic disorders - 25: B Gunnar Wallin: Intraneural recordings of normal and abnormal sympathetic activity in humans - 26: Fion D Bremner and S E Smith: Pupil abnormality in autonomic disorders: detection and occurrence - 27: Sudhansu Chokroverty: Assessment of sleep disturbances in autonomic failure - 28: Phillip A Low and Robert D Fealey: Evaluation of sudomotor function - 29: Soumendra N Datta and Clare J Fowler: Investigation and treatment of bladder dysfunction in diseases affecting the autonomic nervous system - 30: Murray Esler and Gavin Lambert: Biochemical investigation of autonomic function: measurement of catecholamines and metabolites, and the use of spillover and allied techniques to determine regional sympathetic activation - 31: D G Thompson and D L Wingate: Autonomic function and the gastrointestinal tract - 32: Markus Naumann and Christopher Mathias: Treatment of hyperhidrosis - 33: Linda Luxon and Waheeda Pagarkar: Vestibular and autonomic interaction - 34: Timothy M Young and Christopher J Mathias: Cardiovascular effects of water ingestion - 35: Roger Bannister, Valeria Iodice, Ekawat Vichayanrat, and Christopher J Mathias: Clinical features and evaluation of the primary chronic autonomic failure syndromes - 36: David J Brooks: Neuroimaging in autonomic failure syndromes - 37: Margaret R Matthews: Autonomic ganglia and preganglionic neurones in autonomic failure - 38: Roger Bannister, Valeria Iodice and Christopher J Mathias: Management of postural hypotension - 39: Uday Muthane and Andrew J Lees: Treatment of the motor disorders of multiple system atrophy - 40: Pietro Cortelli and Christopher J Mathias: Parkinson's disease and autonomic failure - 41: Heiko Braak and Kelly Del Tredici: Development of Parkinson's disease-related pathology in the enteric and central nervous systems - 42: Janice L Holton and Tamas Revesz: Neuropathology of multiple system atrophy - 43: Nadia Stefanova and Gregor K Wenning: Experimental models to define multiple system atrophy and autonomic failure - 44: Felicia B Axelrod: Familial dysautonomia - 45: Michael E Edmonds: Autonomic failure in diabetes - 46: Christopher J Mathias and Roger Bannister: Dopamine-beta-hydroxylase deficiency: with a note on other genetically determined causes of autonomic failure - 47: Michael Donaghy: Autonomic dysfunction in peripheral nerve disease - 48: Steven Vernino and Angela Vincent: Autoimmune and paraneoplastic autonomic neuropathies - 49: Sinead M Murphy and Mary M Reilly: Hereditary amyloid neuropathy - 50: Martin A Samuels: Introduction to neurocardiology - 51: J Gert van Dijk: Transient loss of consciousness - 52: Roger Hainsworth and Victoria E. Claydon: Syncope and fainting: classification and pathophysiological basis - 53: Rose Anne Kenny: Neurally mediated syncope - 54: John B P Stephenson: Paediatric aspects of neurally mediated syncope - 55: Wilfrid Janig: Pain and the sympathetic nervous system: pathophysiological mechanisms - 56: Krysztof Narkiewicz and Virend K Somers: Sympathetic neural mechanisms in hypertension - 57: Philip A Low: Postural orthostatic tachycardia syndrome - 58: Niels H Secher and Johannes J van Lieshout: Circulatory shock - 59: Christopher J Mathias and Hans L Frankel: Autonomic disturbances in spinal cord lesions - 60: C T Paul Krediet and Wouter Wieling: Situational syncope - 61: Abhay Bajpai and A John Camm: Cardiac causes of syncope - 62: Gary S Francis and Jay N Cohn: Cardiac failure and the autonomic nervous system - 63: Peter D Drummond: Autonomic disorders affecting cutaneous blood flow - 64: Lars Lykke Thomsen and Jes Olesen: Autonomic aspects of migraine: pathophysiology and treatment - 65: Anne L Tonkin and Derek B Frewin: Drugs, chemicals, and toxins that alter autonomic function - 66: Lewis A Lipsitz and Vera Novak: Ageing and the autonomic nervous system - 67: Omer Aziz, Marios Nicolaou, Ara W Darzi: Surgery and the autonomic nervous system - 68: Sanjay Purkayastha, J Anthony Firth, Ara W Darzi: Autonomic Surgical Neuroanatomy - 69: Graeme Eisenhofer, Jacques W M Lenders, William M Manger, Karel Pacak: Phaeochromocytoma: a clinical chameleon
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