Diagnosis and Management of Peripheral Nerve Disorders

Edited by Jerry R. Mendell (Professor and Chair, Department of Neurology, Ohio State University, Columbus, USA); John T. Kissel (Professor of Neurology, Ohio State University, Columbus, USA); David R. Cornblath (Professor of Neurology, Johns Hopkins University School of Medicine, USA). Series: Contemporary Neurology Series, v. 59 Peripheral neuropathies represent a challenging subject for most physicians. This comprehensive guide to peripheral neuropathies includes concise information on the clinical, electrophysiological, pathological, pathogenic and treatment aspects of the most important disorders. New molecular and serologic diagnostic tests are discussed. Sections are devoted to nerve and skin biopsy techniques and findings, quantitative sensory and autonomic reflex tests. Case examples are used liberally throughout the text. The editors are experienced clinicians that bring complementary knowledge to each of the subjects. Additional authors have been handpicked for specific topics which add to the usefulness of the edition. CONTENTS Evaluation of the patient with peripheral neuropathies - the challenges; clues to diagnosis of peripheral neuropathy - the history and examination of the patient; electrodiagnostic evaluation of the peripheral neuropathy patient; evaluation of the peripheral neuropathy patient using quantitative sensory testing; evaluation of the peripheral neuropathy patient using reflex tests; the role of autoantibody testing; the role of peripheral nerve and skin biopsies; approach to painful peripheral neuropathies; Guillain-Barre syndrome; chronic inflammatory demyelineating polyradiculoneuropathy; multifocal motor neuropathy; vasculitic neuropathy; peripheral neuropathies associated with connective tissue diseases; sarcoid peripheral neuropathy; neuropathies associated with monoclonal gammopathies; toxic neuropathies - drugs, metals and alcohol; porphyric neuropathy; critical illness polyneuropathy and related conditions; diabetic neuropathies; peripheral neuropathy associated with HIV infection; hereditary motor and sensory neuropathies; hereditary sensory and autonomic neuropathies; familial amyloid polyneuropathies; peripheral neuropathies associated with peroxisomal defects - Refsum disease and adrenomyeloneuropathy; galactosidase A deficiency - Fabry disease; lipids and lippoproteins; vitamin deficiencies - cobalamin (vitamin B12), vitamin E (tocopherol), & thiamine (vitamin B1); leprous neuropathy; neuropathies associated with organ system failure, organ transplantation, metabolic disorders, and cancer; entrapment neuropathies. (Part contents).