Kidney Protection

Kidney disease affects approximately ten percent of the population worldwide, with more than 2.6 million individuals estimated to be receiving renal replacement therapy. Chronic kidney disease (CKD) is fast becoming a major public health issue, with increasing incidence and death rates throughout the world. Many strategies have been proposed to reduce the growing burden of kidney disease; but while early identification and improved access to renal replacement therapies and transplantation are important, they are unlikely to solve this enormous problem. Efforts focused on primary prevention, protection, and slowing the progression of kidney disease are needed as well. Renal protection is a vital and critical component of protecting the kidneys, promoting recovery, and preventing further renal loss, yet observational data suggests that awareness of renal protection remains low and the concept of renal protection under-recognized..

Kidney Protection: A Practical Guide to Preserving Renal Function in Acute and Chronic Disease is a clinically focused review that aims to address this awareness and knowledge gap. It assembles clinically pertinent information in a concise and lucid format with the goal of helping the clinician protect the kidneys, whether in the ICU, perioperative, or out-patient setting. The authors' interdisciplinary approach is inclusive of nephrology, urology, critical care, anesthesia, and emergency medicine. Chapters review understanding kidney disease, general concepts in protecting renal function, patient selection, assessment, pharmacologic issues, and kidney protection in systemic illness. The latest evidence-based practical guidelines for optimal renal outcomes are also included.

Table of Contents

I. Understanding Kidney Disease
1. Epidemiology and Etiology of Kidney disease
Cecile Couchoud
Sahar Bayat
2. Pathogenesis of Acute Kidney Injury
David Basile
Babu Padanilam
3. Adaptations in Acute Kidney Injury: Progression to Chronic Kidney Disease
Navin Jaipaul
4. Risk factors for Chronic Kidney Disease
Hania Kassem
Bernard jaar
5. Senescence of the Kidney
Eoin D. O'Sullivan
David Ferenbach
6. The kidney in Pregnancy
Samuel Mon-Wei Yu
Anjali Acharya
II. Assessment of Kidney Disease
7. Laboratory Investigation of the Kidney
Timothy Larson
8. Imaging of the Kidney
David C. Wymer
9. Fundamentals of Kidney Pathology
Serena Maria Bagnasco
III. General Concepts in Protecting Kidney Function
10. Pharmacologic renal protection
Wael Hussein
Austin Stack
11. Evaluation and Management of Acute Kidney Injury
Bhagwan Dass
William Hahn
Rajesh Mohandas
12. Slowing progression of Chronic Kidney Disease
Martine Pollack-Zollman
Joseph Vassalotti
13. Renal Artery Stenosis and Revascularization
Joseph Messana
Raymond R. Townsend
14. Environmental toxins and the Kidney
Joshua King
Bernard Jaar
15. Peri-operative Renal Protection
Sapna Shah
Vijay Lapsia
16. Renal protection in Critically Ill patients
Ryan W. Haines
John R. Prowle
17. Obstructive Uropathies Priya Deshpande
Suchita Sharma
18. Nephron Sparing Surgery
Stefano Puliatti
Nancy Ferrari
Bernardo Rocco
Giampaolo Bianchi
Salvatore Micali
19. Choice of Renal Replacement Therapy
Sara Samoni
Claudio Ronco
20. Preserving Residual Renal Function
Miten G. Dhruve
Joanne Bargman
IV. Drugs and Kidney Function
21. Principles of Drug Therapy in Reduced Kidney Function
Tim Nguyen
Tran Tran
Thomas Dowling
22. Acute Kidney Injury from Therapeutic Agents
Daphne Knicely, Michael J. Choi, Sumeska Thavarajah
23. Immunological Agents in the Treatment of Glomerulonephritis Samira Farouk
Jonathan Winston
24. NSAIDs and the Kidney Tonia Kim
Chan, Lili
25. Contrast and the Kidney
Swapnil Hiremath
26. Chemotherapeutic agents and the Kidney
Umut Selamet
Ramy M. Hanna
Anjay Rastogi
Ala Abudayyeh
27. Poisonings & Intoxications
Nikolas Harbord
Muhammed S. Akhter
V. Kidney Protection in systemic illness
28. Diabetes Mellitus and the Kidney
John He
29. Hypertension and the Kidney
Rupinder K Sodhi
Marie D. Philipneri
Paul G. Schmitz
30. Cardiovascular Protection in Chronic Kidney Disease
Jonathan W. Waks
Rulan S. Parekh2, MD,
Larisa G. Tereschenko
31. Lupus Nephritis
Aisha Shaikh
Kirk Campbell
32. Thrombotic Microangiopathies
Lewis Kaufman
33. Systemic Inflammatory Diseases and the Kidney
Manny Trujillo
Duvuru Geetha
34. The Kidney in patients with Cancer
Ramnika Gumber
Akash Sethi
Jonathan Hogan
35. Cast Nephropathy in Plasma cell Dyscrasias
Sandhya Manohar
Nelson Leung
36. Sickle Cell Nephropathy
Katia Lopez Revuelta
Maria Pilar Ricard Andres
37. Kidney disease in HIV infection and Treatment
Christina Wyatt
38. Cystic Kidney Diseases
Fouad T Chebib
Vincente Torres
39. Hepatitis Associated Glomerulonephritis
Julie Belliere,
Stanislas Faguer,
Nassim Kamar
40. Hepatorenal syndrome
François Durand, Claire Francoz, Joseph DiNorcia, Yuri S. Genyk, Mitra K. Nadim
41. Cardiorenal syndrome
Edward Ross
Uyanga Batnyam
Abdo Asmar
42. Cardiac surgery and the Kidney
Annette L Mazzone
Jonathan Gleadle
43. Tubulointerstitial Nephropathies
Abhilash Koratala
Girish Singhania
Ahsan Ejaz
44. Cholesterol Embolism
Alain Meyrier
VI. Kidney Protection in Transplantation
45. High-risk Kidney Transplantation
Madhav Menon
Susan Lerner
46. Recurrence of Primary Glomerular Disease Post Kidney Transplantation
Nada Alachkar
John Manello Dieck