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Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair. This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. # Comprehensive review of the latest developments in neuroinflammation # Includes contributions from leading authorities Alireza Minagar , MD, FAAN, Louisiana State University Health Sciences Center, Shreveport, LA, USA Table of Contents 1. Multiple Sclerosis 2. Optic neuritis 3. Transverse myelitis 4. Ischemic demyelination 5. Acute disseminated encephalomyelitis 6. Neurosarcoidosis 7. Balo concentric sclerosis 8. Neuromyelitis optica (Devic's disease) 9. Necrotizing myelopathy 10. Susac syndrome 11. Central nervous system vasculitis 12. Neuropsychiatric SLE 13. Progressive multifocal leukoencephalopathy 14. Antiphospholipid antibody syndrome 15. Current treatments for multiple sclerosis