Development of the Nervous System

Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the Second Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. A thoroughly revised chapter 10 adds a specific emphasis on the emerging understanding of behavioral and cognitive development as informed by the molecular and cellular knowledge introduced in this book. The original, artist-rendered drawings, now in full color, have all been reviewed, many revised and a number of new graphics have been added. This new edition is the only up to date developmental neuroscience textbook for undergraduate and graduate level students for courses offered in Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology programs. By Dan H. Sanes, New York University, New York, U.S.A.; Thomas A. Reh, University of Washington, Seattle, U.S.A. and William A. Harris, University of Cambridge, U.K.