Principles & Practice of Mechanical Ventilation, 3e provides comprehensive, authoritative coverage of all the clinical, pharmacological, and technical issues surrounding the use of mechanical ventilation. Editor Martin J. Tobin ' past editor-in-chief of the American Journal of Respiratory and Critical Care Medicine ' has enlisted more than 100 authors, all of whom are at the forefront of research in their chosen subfield in order to provide the most authoritative and up-to-date information possible. No other text so thoroughly and comprehensively explores the myriad advances in modes and methodologies that have occurred in this ever-changing field as this cornerstone text. Features Each chapter has been extensively revised to reflect the latest research A strong focus on the biomedical principles that govern ventilator management Expert insights from contributors in critical care, pulmonary medicine, anesthesiology, surgery, basic science, provide a unique multidisciplinary approach 68 chapters that explore every important aspect of mechanical ventilation, including: Conventional and unconventional methods of ventilator support; Noninvasive methods of ventilator support; Unconventional methods of ventilator support; Physiologic effect of mechanical ventilation; Complications in ventilator supported patients; Weaning of ventilator-support; Management of the ventilator-supported patient; Adjunctive therapy, including fluid management, inhaled antibiotic therapy, and bronchodilator therapy; Ethics and economics Principles & Practice of Mechanical Ventilation, 3e comprehensively covers the principles and practice of keeping patients alive through the use of mechanical ventilation, along with related pharmacological and technical issues. Martin J. Tobin, MD is Professor of Medicine, Pulmonary and Critical Care Medicine at Loyola University Health Systems in Chicago, Illinois Table of contents PART I: HISTORICAL BACKGROUND 1. Historical Perspective on the Development of Mechanical Ventilation PART II: PHYSICAL BASIS OF MECHANICAL VENTILATION 2. Classification of Mechanical Ventilators 3. Basic Principles of Ventilator Machinery 4. Equipment Required for Home Mechanical Ventilation PART III: INDICATIONS 5. Indications for Mechanical Ventilation PART IV: CONVENTIONAL METHODS OF VENTILATOR SUPPORT 6. Setting the Ventilator 7. Assist-Control Ventilation 8. Intermittent Mandatory Ventilation 9. Pressure Support Ventilation 10. Positive End-Expiratory Pressure PART V: ALTERNATIVE METHODS OF VENTILATOR SUPPORT 11. Pressure-Controlled and Inverse Ratio Ventilation 12. Airway Pressure Release Ventilation 13. Proportional Assist Ventilation 14. Closed-Loop Ventilation 15. Permissive Hypercapnia 16. New Modes PART VI: NONINVASIVE METHODS OF VENTILATOR SUPPORT 17. Negative Pressure Ventilation 18. Use of the Rocking Bed, Pneumobelt, and Other Noninvasive Aids to Ventilation 19. Noninvasive Mechanical Ventilation by Nasal or Face Mask PART VII: UNCONVENTIONAL METHODS OF VENTILATOR SUPPORT 20. High Frequency Ventilation 21. Extracorporeal Membrane Oxygenation and Intravascular Membrane Oxygenation 22. Extracorporeal CO2 Removal for ARDS and the Evaluation of New Therapy 23. Liquid Ventilation 24. Transtracheal Gas Insufflation PART VIII: VENTILATOR SUPPORT IN SPECIFIC SETTINGS 25. Mechanical Ventilation in the Neonatal and Pediatric Setting 26. Delivery of Mechanical Ventilation during General Anesthesia 27. Independent Lung Ventilation 28. Delivery of Mechanical Ventilation during Resuscitation 29. Transport of the Ventilator-Supported 30. Home Mechanical Ventilation 31. Mechanical Ventilation in ARDS 32. Mechanical Ventilation in Asthma 33. Mechanical Ventilation in Chronic Obstructive Pulmonary Disease 34. Mechanical Ventilation in Neuromuscular Disease 35. Chronic Ventilator Facilities (LTAC) 36. Mechanical Ventilation outside the ICU PART IX: PHYSIOLOGIC EFFECT OF MECHANICAL VENTILATION 37. Effect of Mechanical Ventilation on the Control of Breathing 38. Heart-Lung Interactions 39. Effect of Mechanical Ventilation on Gas Exchange PART X: ARTIFICIAL AIRWAYS AND MANAGEMENT 40. Airway Management 41. Complications of Translaryngeal Intubation 42. Care of the Mechanically Ventilated Patient with a Tracheotomy PART XI: COMPLICATIONS IN VENTILATOR SUPPORTED PATIENTS 43. Complications Associated with Mechanical Ventilation 44. Ventilator-Induced Injury 45. Barotrauma and Bronchopleura 46. Oxygen Toxicity 47. Pneumonia in the Ventilator-Dependent Patient 48. Sinus Infections 49. Molecular-biological Injury PART XII: EVALUATION AND MONITORING OF VENTILATOR-SUPPORTED PATIENTS 50. Imaging the Mechanically Ventilated Patient 51. Monitoring during Mechanical Ventilation 52. Protocol-Based Management PART XIII: MANAGEMENT OF THE VENTILATOR-SUPPORTED PATIENT 53. Technical Aspects of the Patient-Ventilator Interface 54. Patient Positioning in Acute Respiratory Failure 55. Neuromuscular Blockade, Sedation, and Pain Control 56. Humidification 57. Management of the Patient Who is 'Fighting the Ventilator' 58. Psychological Problems in the Ventilator-Dependent Patient 59. Discontinuation of Mechanical Ventilation 60. Anesthesiology and Intraoperative Mechanical Ventilation PART XIV: ADJUNCTIVE THERAPY 61. Surfactant 62. Nitric Oxide as an Adjunct 63. Diaphragmatic Pacer 64. Bronchodilator Therapy 65 Inhaled Antibiotic Therapy PART XV: ETHICS AND ECONOMICS 66. Withholding and Withdrawing Ventilator Support: Ethical Problems 67. Economics of Ventilator Care 68. Purchasing a Ventilator 69. Effect of Mechanical Ventilation on Outcome
