Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field.
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New to this edition
Now in full color, with special design treatment for at-a-glance pediatric content, helping to distinguish the pediatric content.
Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer.
New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more.
Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus.
New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read.
Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Table of Contents:
1 PRINCIPLES OF ENDOCRINOLOGY
2 CONTROL OF HORMONE GENE EXPRESSION
3 CONTROL OF HORMONE SECRETION
4 APPLICATIONS OF GENETICS IN ENDOCRINOLOGY
5 DEVELOPMENT OF THE PITUITARY
6 PROLACTIN
7 DISORDERS OF PROLACTIN SECRETION AND PROLACTINOMAS
8 ADRENOCORTICOTROPIC HORMONE
9 ENDOCRINE RHYTHMS, THE SLEEP-WAKE CYCLE, AND BIOLOGICAL CLOCKS
10 HYPOTHALAMIC SYNDROMES
11 HYPOPITUITARISM
12 ACROMEGALY
13 CUSHING’S SYNDROME
14 CLINICALLY NONFUNCTIONING SELLAR MASSES
15 TSH-PRODUCING ADENOMAS
16 PITUITARY SURGERY
17 CHILDHOOD HYPOTHALAMIC AND PITUITARY TUMORS
18 VASOPRESSIN, DIABETES INSIPIDUS, AND THE SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION
19 THE PINEAL GLAND AND MELATONIN
20 GROWTH HORMONE: STRUCTURE, FUNCTION AND REGULATION OF SECRETION
21 INSULIN-LIKE GROWTH FACTOR-1
22 SOMATIC GROWTH AND MATURATION
23 GROWTH HORMONE DEFICIENCY IN CHILDREN
24 PERFORMANCE ENHANCING HORMONES IN SPORTS DOPING
25 APPETITE REGULATION AND THERMOGENESIS
26 OBESITY: The Problem and Its Management
27 Bariatirc Surgery
28 GENETIC SYNDROMES ASSOCIATED WITH OBESITY
29 ANOREXIA NERVOSA, BULIMIA NERVOSA, AND OTHER EATING DISORDERS
30 DEVELOPMENT OF THE ENDOCRINE PANCREAS
31 ISLET HORMONE SYNTHESIS AND SECRETION
32 THE PHYSIOLOGY OF INSULIN SECRETION
33 THE MECHANISMS OF INSULIN ACTION
34 GLUCAGON AND THE GLUCAGON-LIKE PEPTIDES
35 REGULATION OF INTERMEDIATORY METABOLISM DURING FASTING AND FEEDING
36 THE ADIPOCYTE AND METABOLISM
37 LIPODYSTROPHY SYNDROMES
38 CLASSIFICATION AND DIAGNOSIS OF DIABETES MELLITUS
39 TYPE 1 DIABETES: PATHOGENESIS
40 TYPE 2 DIABETES: PATHOGENESIS
41 LIPOPROTEIN METABOLISM AND THE TREATMENT OF LIPID DISORDERS
42 HYPERGLYCEMIA SECONDARY TO NONDIABETIC CONDITIONS AND THERAPIES
43 THE METABOLIC SYNDROME
44 MANAGEMENT OF TYPE 1 DIABETES IN ADULTS
45 DIABETES AND PREGNANCY
46 KETOACIDOSIS AND HYPEROSMOLAR COMA
47 HYPOGLYCEMIA AND HYPOGLYCEMIC SYNDROMES
48 MANAGEMENT OF TYPE 2 DIABETES
49 MANAGEMENT OF DIABETES IN CHILDREN
50 BETA CELL REPLACEMENT AND REGENERATION
51 DIABETES AND LONG-TERM COMPLICATIONS
52 DIABETIC EYE DISEASE
53 DIABETIC NEUROPTHY
54 DIABETIC NEPHROPATHY
55 DIABETIC FOOT AND VASCULAR COMPLICATIONS
56 PARATHYROID HORMONE
57 PARATHYROID HORMONE-RELATED PROTEIN
58 CALCITONIN
59 VITAMIN D
60 BONE DEVELOPMENT AND REMODELING
61 HYPERCALCEMIA & HYPOCALCEMIA: GENETIC & OTHER CAUSES
62 HYPERPHOSPHOTEMIA & HYPOPHOSPHOTEMIA: GENETIC & OTHER CAUSES
63 PRIMARY HYPERPARATHYROIDISM
64 MALIGNANCY-ASSOCIATED HYPERCALCEMIA AND MEDICAL MANAGEMENT
65 SURGICAL MANAGEMENT OF HYPERPARATHYROIDISM
66 PSEUDOHYPOPARATHYROIDISM, ALBRIGHT’S HEREDITARY OSTEODYSTROPHY, AND PROGRESSIVE OSSEOUS HETEROPLASIA
67 GENETIC DEFECTS IN VITAMIN D METABOLISM AND ACTION
68 HEREDITARY DISORDERS OF THE SKELETON
69 OSTEOPOROSIS
70 MINERAL AND BONE DISORDERS IN CHRONIC RENAL DISEASE:
71 OSTEOMALACIA AND RICKETS
72 PAGET’S DISEASE OF BONE
73 ANATOMY AND DEVELOPMENT OF THE THYROID
74 THYROID-STIMULATING HORMONE: Physiology and Secretion
75 THYROID HORMONE BIOSYNTHESIS
76 THYROID HORMONE METABOLISM AND TRANSPORT
77 THYROID HORMONE ACTION
78 THYROID FUNCTION TESTING
79 THYROID IMAGING
80 Thyroid Fine Needle Aspiration and Cytological Diagnosis
81 AUTOIMMUNE THYROID DISEASE
82 GRAVES’ DISEASE
83 GRAVES’ OPHTHALMOPATHY
84 DIAGNOSIS AND TREATMENT OF THYROID DISEASE DURING PREGNANCY
85 AUTONOMOUSLY FUNCTIONING THYROID NODULES AND OTHER CAUSES OF THYROTOXICOSIS
86 CHRONIC (HASHIMOTO’S) THYROIDITIS
87 SUBACUTE AND RIEDEL’S THYROIDITIS
88 HYPOTHYROIDISM AND MYXEDEMA COMA
89 NONTHYROIDAL ILLNESS SYNDROME: A FORM OF HYPOTHYROIDISM
90 MULTINODULAR GOITER
91 IODINE DEFICIENCY DISORDERS
92 THYROID NEOPLASIA
93 THYROID-STIMULATING HORMONE RECEPTOR MUTATIONS
94 Genetic Defects in Thyroid Hormone Synthesis and Action
95 Defects in Thyroid Hormone: Transport & Action
96 SURGERY OF THE THYROID
97 ADRENAL STEROIDOGENESIS
98 GLUCOCORTICOID RECEPTORS+D128
99 GLUCOCORTICOID: Physiology & Pharmacology
100 GLUCOCORTICOID THERAPY
101 ALDOSTERONE SECRETION AND ACTION
102 ADRENAL INSUFFICIENCY
103 ADRENAL CAUSES OF HYPERCORTISOLISM
104 DEFECTS OF ADRENAL STEROIDOGENESIS
105 ADRENARCHE AND ADRENOPAUSE
106 ADRENAL GLAND IMAGING
107 ADRENOCORTICAL CARCINOMA
108 PRIMARY MINERALOCORTICOID EXCESS SYNDROMES AND HYPERTENSION
109 MINERALOCORTICOID DEFICIENCY
110 PHEOCHROMOCYTOMA
111 ADRENAL SURGERY
112 HYPONATREMIA AND HYPERNATREMIA
113 ORTHOSTATIC HYPOTENSION AND ORTHOSTATIC INTOLERANCE
114 ENDOCRINE ASPECTS OF CRITICAL CARE MEDICINE
115 GONADOTROPIN-RELEASING HORMONES
116 GONADOTROPINS-REGULATION OF SYNTHESIS AND SECRETION
117 GONADAL PEPTIDES: INHIBINS, ACTIVINS, FOLLISTATIN, MULLERIAN-INHIBITING SUBSTANCE
118 GENETIC BASIS OF GONADAL AND GENITAL DEVELOPMENT
119 DIAGNOSIS AND TREATMENT OF DISORDERS OF SEXUAL DEVELOPMENT
120 ENDOCRINOLOGY OF SEXUAL MATURATION AND PUBERTY
121 PRECOCIOUS PUBERTY
122 DELAYED PUBERTY
123 SEXUAL DYSFUNCTION
124 THE ENDOCRINOLOGY OF SEXUAL BEHAVIOR AND GENDER IDENTITY
125 FOLLICULOGENESIS, OVULATION, AND LUTEOGENESIS
126 OVARIAN HORMONE SYNTHESIS
127 ESTROGEN AND PROGESTERONE ACTION
128 HORMONAL CONTROL OF BREAST DEVELOPMENT
129 MENSTRUAL CYCLE AND DISORDERS OF OVULATION
130 ENDOMETRIOSIS & UTERINE FIBROIDS
131 ENDOCRINOLOGIC ASPECTS OF BENIGN AND MALIGNANT BREAST DISEASE
132 FEMALE INFERTILITY
133 POLYCYSTIC OVARY SYNDROME, HYPERANDROGENISM & HIRSUTISM
134 CONTRACEPTION
135 MENOPAUSE
136 SPERMATOGENESIS
137 TESTICULAR DYSGENESIS SYNDROME, CRYPTORCHIDISM, HYPOSPADIAS, AND TESTICULAR TUMORS
138 ANDROGEN ACTION & PHARMACOLOGY
139 ANDROGEN DEFICIENCY DISORDERS
140 GYNECOMASTIA
141 MALE INFERTILITY
142 MALE CONTRACEPTION
143 ENDOCRINOLOGY OF THE PROSTATE
144 THE ENDOCRINOLOGY OF HUMAN PREGNANCY AND PARTURITION
145 FETAL AND NEONATAL ENDOCRINOLOGY
146 HORMONAL CHANGES AND ENDOCRINE TESTING IN PREGNANCY
147 AUTOIMMUNE POLYGLANDULAR SYNDROMES
148 MULTIPLE ENDOCRINE NEOPLASIA TYPE 1
149 MULTIPLE ENDOCRINE NEOPLASIA TYPE 2
150 NEUROENDOCRINE TUMOR SYNDROMES
151 CARCINOID SYNDROME
152 ECTOPIC HORMONE SYNDROMES
153 ENDOCRINE DISRUPTERS
154 ENDOCRINE TESTING
